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Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface.
Huang J, Kang BH, Pancera M, Lee JH, Tong T, Feng Y, Imamichi H, Georgiev IS, Chuang GY, Druz A, Doria-Rose NA, Laub L, Sliepen K, van Gils MJ, de la Peña AT, Derking R, Klasse PJ, Migueles SA, Bailer RT, Alam M, Pugach P, Haynes BF, Wyatt RT, Sanders RW, Binley JM, Ward AB, Mascola JR, Kwong PD, Connors M. Huang J, et al. Nature. 2014 Nov 6;515(7525):138-42. doi: 10.1038/nature13601. Epub 2014 Sep 3. Nature. 2014. PMID: 25186731 Free PMC article.
Antibody-secreting B cells in HIV infection.
Doria-Rose NA, Connors M. Doria-Rose NA, et al. Curr Opin HIV AIDS. 2009 Sep;4(5):426-30. doi: 10.1097/COH.0b013e32832d9fac. Curr Opin HIV AIDS. 2009. PMID: 20048707 Free PMC article. Review.
Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1.
Wu X, Yang ZY, Li Y, Hogerkorp CM, Schief WR, Seaman MS, Zhou T, Schmidt SD, Wu L, Xu L, Longo NS, McKee K, O'Dell S, Louder MK, Wycuff DL, Feng Y, Nason M, Doria-Rose N, Connors M, Kwong PD, Roederer M, Wyatt RT, Nabel GJ, Mascola JR. Wu X, et al. Science. 2010 Aug 13;329(5993):856-61. doi: 10.1126/science.1187659. Epub 2010 Jul 8. Science. 2010. PMID: 20616233 Free PMC article.
Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing.
Wu X, Zhou T, Zhu J, Zhang B, Georgiev I, Wang C, Chen X, Longo NS, Louder M, McKee K, O'Dell S, Perfetto S, Schmidt SD, Shi W, Wu L, Yang Y, Yang ZY, Yang Z, Zhang Z, Bonsignori M, Crump JA, Kapiga SH, Sam NE, Haynes BF, Simek M, Burton DR, Koff WC, Doria-Rose NA, Connors M; NISC Comparative Sequencing Program; Mullikin JC, Nabel GJ, Roederer M, Shapiro L, Kwong PD, Mascola JR. Wu X, et al. Science. 2011 Sep 16;333(6049):1593-602. doi: 10.1126/science.1207532. Epub 2011 Aug 11. Science. 2011. PMID: 21835983 Free PMC article.
Comprehensive analysis of unique cases with extraordinary control over HIV replication.
Mendoza D, Johnson SA, Peterson BA, Natarajan V, Salgado M, Dewar RL, Burbelo PD, Doria-Rose NA, Graf EH, Greenwald JH, Hodge JN, Thompson WL, Cogliano NA, Chairez CL, Rehm CA, Jones S, Hallahan CW, Kovacs JA, Sereti I, Sued O, Peel SA, O'Connell RJ, O'Doherty U, Chun TW, Connors M, Migueles SA. Mendoza D, et al. Blood. 2012 May 17;119(20):4645-55. doi: 10.1182/blood-2011-10-381996. Epub 2012 Apr 5. Blood. 2012. PMID: 22490332 Free PMC article.
173 results