The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity.
Wieczorek M, Tcherkezian J, Bernier C, Prota AE, Chaaban S, Rolland Y, Godbout C, Hancock MA, Arezzo JC, Ocal O, Rocha C, Olieric N, Hall A, Ding H, Bramoullé A, Annis MG, Zogopoulos G, Harran PG, Wilkie TM, Brekken RA, Siegel PM, Steinmetz MO, Shore GC, Brouhard GJ, Roulston A.
Wieczorek M, et al. Among authors: bramoulle a.
Sci Transl Med. 2016 Nov 16;8(365):365ra159. doi: 10.1126/scitranslmed.aag1093.
Sci Transl Med. 2016.
PMID: 27856798
Free PMC article.