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Discovery of 5-chloro-4-((1-(5-chloropyrimidin-2-yl)piperidin-4-yl)oxy)-1-(2-fluoro-4-(methylsulfonyl)phenyl)pyridin-2(1H)-one (BMS-903452), an antidiabetic clinical candidate targeting GPR119.
Wacker DA, Wang Y, Broekema M, Rossi K, O'Connor S, Hong Z, Wu G, Malmstrom SE, Hung CP, LaMarre L, Chimalakonda A, Zhang L, Xin L, Cai H, Chu C, Boehm S, Zalaznick J, Ponticiello R, Sereda L, Han SP, Zebo R, Zinker B, Luk CE, Wong R, Everlof G, Li YX, Wu CK, Lee M, Griffen S, Miller KJ, Krupinski J, Robl JA. Wacker DA, et al. Among authors: wong r. J Med Chem. 2014 Sep 25;57(18):7499-508. doi: 10.1021/jm501175v. Epub 2014 Sep 10. J Med Chem. 2014. PMID: 25208139
An integrated multiplatform bioanalytical strategy for antibody-drug conjugates: a novel case study.
Myler H, Rangan VS, Wang J, Kozhich A, Cummings JA, Neely R, Dail D, Liu A, Wang B, Vezina HE, Freebern W, Sung MC, Passmore D, Deshpande S, Kempe T, Gu H, Saewert M, Manney A, Lute J, Zambito F, Wong RL, Piccoli SP, Aubry AF, Pillutla R, Arnold M, DeSilva B. Myler H, et al. Among authors: wong rl. Bioanalysis. 2015;7(13):1569-82. doi: 10.4155/bio.15.80. Bioanalysis. 2015. PMID: 26226308
Antibody-drug conjugate bioanalysis using LB-LC-MS/MS hybrid assays: strategies, methodology and correlation to ligand-binding assays.
Wang J, Gu H, Liu A, Kozhich A, Rangan V, Myler H, Luo L, Wong R, Sun H, Wang B, Vezina HE, Deshpande S, Zhang Y, Yang Z, Olah TV, Aubry AF, Arnold ME, Pillutla R, DeSilva B. Wang J, et al. Among authors: wong r. Bioanalysis. 2016 Jul;8(13):1383-401. doi: 10.4155/bio-2016-0017. Epub 2016 Jun 9. Bioanalysis. 2016. PMID: 27277879
Quantitative bioanalysis of antibody-conjugated payload in monkey plasma using a hybrid immuno-capture LC-MS/MS approach: Assay development, validation, and a case study.
Liu A, Kozhich A, Passmore D, Gu H, Wong R, Zambito F, Rangan VS, Myler H, Aubry AF, Arnold ME, Wang J. Liu A, et al. Among authors: wong r. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 1;1002:54-62. doi: 10.1016/j.jchromb.2015.08.007. Epub 2015 Aug 12. J Chromatogr B Analyt Technol Biomed Life Sci. 2015. PMID: 26310897
Increased mortality from alcohol use disorder, alcohol-associated liver disease, and liver cancer from alcohol among older adults in the United States: 2000 to 2021.
Danpanichkul P, Duangsonk K, Tham EKJ, Tothanarungroj P, Auttapracha T, Prasitsumrit V, Sim B, Tung D, Barba R, Wong RJ, Leggio L, Yang JD, Chen VL, Noureddin M, Díaz LA, Arab JP, Wijarnpreecha K, Liangpunsakul S. Danpanichkul P, et al. Among authors: wong rj. Alcohol Clin Exp Res (Hoboken). 2024 Dec 19. doi: 10.1111/acer.15516. Online ahead of print. Alcohol Clin Exp Res (Hoboken). 2024. PMID: 39701596
Mexican Health and Aging Study Biomarker and Genetic Data Profile.
Samper-Ternent R, Zazueta-Borboa JD, Michaels-Obregon A, Reyes-Dumeyer D, Barral S, Tosto G, Wong R. Samper-Ternent R, et al. Among authors: wong r. J Gerontol A Biol Sci Med Sci. 2024 Dec 11;80(1):glae270. doi: 10.1093/gerona/glae270. J Gerontol A Biol Sci Med Sci. 2024. PMID: 39692026
5,620 results