Leng Y - Search Results

1

A Bim-targeting strategy overcomes adaptive bortezomib resistance in myeloma through a novel link between autophagy and apoptosis.

Chen S, Zhang Y, Zhou L, Leng Y, Lin H, Kmieciak M, Pei XY, Jones R, Orlowski RZ, Dai Y, Grant S. Chen S, et al. Among authors: leng y. Blood. 2014 Oct 23;124(17):2687-97. doi: 10.1182/blood-2014-03-564534. Epub 2014 Sep 10. Blood. 2014. PMID: 25208888 Free PMC article.

2

Targeting SQSTM1/p62 induces cargo loading failure and converts autophagy to apoptosis via NBK/Bik.

Chen S, Zhou L, Zhang Y, Leng Y, Pei XY, Lin H, Jones R, Orlowski RZ, Dai Y, Grant S. Chen S, et al. Among authors: leng y. Mol Cell Biol. 2014 Sep 15;34(18):3435-49. doi: 10.1128/MCB.01383-13. Epub 2014 Jul 7. Mol Cell Biol. 2014. PMID: 25002530 Free PMC article.

3

A regimen combining the Wee1 inhibitor AZD1775 with HDAC inhibitors targets human acute myeloid leukemia cells harboring various genetic mutations.

Zhou L, Zhang Y, Chen S, Kmieciak M, Leng Y, Lin H, Rizzo KA, Dumur CI, Ferreira-Gonzalez A, Dai Y, Grant S. Zhou L, et al. Among authors: leng y. Leukemia. 2015 Apr;29(4):807-18. doi: 10.1038/leu.2014.296. Epub 2014 Oct 6. Leukemia. 2015. PMID: 25283841 Free PMC article.

4

The NAE inhibitor pevonedistat interacts with the HDAC inhibitor belinostat to target AML cells by disrupting the DDR.

Zhou L, Chen S, Zhang Y, Kmieciak M, Leng Y, Li L, Lin H, Rizzo KA, Dumur CI, Ferreira-Gonzalez A, Rahmani M, Povirk L, Chalasani S, Berger AJ, Dai Y, Grant S. Zhou L, et al. Among authors: leng y. Blood. 2016 May 5;127(18):2219-30. doi: 10.1182/blood-2015-06-653717. Epub 2016 Feb 5. Blood. 2016. PMID: 26851293 Free PMC article.

5

Positive transcription elongation factor b (P-TEFb) is a therapeutic target in human multiple myeloma.

Zhang Y, Zhou L, Leng Y, Dai Y, Orlowski RZ, Grant S. Zhang Y, et al. Among authors: leng y. Oncotarget. 2017 Aug 1;8(35):59476-59491. doi: 10.18632/oncotarget.19761. eCollection 2017 Aug 29. Oncotarget. 2017. PMID: 28938651 Free PMC article.

6

The IAP antagonist birinapant potentiates bortezomib anti-myeloma activity in vitro and in vivo.

Zhou L, Zhang Y, Leng Y, Dai Y, Kmieciak M, Kramer L, Sharma K, Wang Y, Craun W, Grant S. Zhou L, et al. Among authors: leng y. J Hematol Oncol. 2019 Mar 7;12(1):25. doi: 10.1186/s13045-019-0713-x. J Hematol Oncol. 2019. PMID: 30845975 Free PMC article.

7

Mechanisms underlying synergism between circularized tumor necrosis factor-related apoptosis inducing ligand and bortezomib in bortezomib-sensitive or -resistant myeloma cells.

Leng Y, Hu X, Li L, Nkwocha J, Satta T, Sharma K, Kmeiciak M, Zhou H, Zhang Z, Zhou L, Chen W, Grant S. Leng Y, et al. Hematol Oncol. 2022 Dec;40(5):999-1008. doi: 10.1002/hon.3045. Epub 2022 Jul 14. Hematol Oncol. 2022. PMID: 35789025 Free PMC article.

8

A Report of 134 Newly Diagnosed Multiple Myeloma Patients with Renal Impairment.

Liu A, Yang G, Geng C, Wang H, Li L, Li Y, Wu Y, Tian Y, Leng Y, Wang G, Gao W, Chen W. Liu A, et al. Among authors: leng y. Acta Haematol. 2016;135(3):140-5. doi: 10.1159/000440935. Epub 2015 Nov 21. Acta Haematol. 2016. PMID: 26587903

9

Autoantibodies against β₁-adrenergic receptor: response to induction therapy with bortezomib-containing regimens for multiple myeloma patients.

Gao W, Guo WJ, Hou DY, Yang GZ, Wu Y, Li YC, Leng Y, Tang Y, Xu L, Liu JM, Wang H, Wang X, Zhang J, Zhao WS, Chen WM, Zhang L. Gao W, et al. Among authors: leng y. Leuk Lymphoma. 2018 Mar;59(3):717-724. doi: 10.1080/10428194.2017.1344904. Epub 2017 Jul 6. Leuk Lymphoma. 2018. PMID: 28679329

10

Prognostic value of t(4;14) translocation in newly diagnosed multiple myeloma patients in novel agent era.

Geng C, Yang G, Zhou H, Wang H, Li Y, Leng Y, Zhang Z, Jian Y, Chen W. Geng C, et al. Among authors: leng y. Hematology. 2023 Dec;28(1):2161222. doi: 10.1080/16078454.2022.2161222. Hematology. 2023. PMID: 36607148 Free article.

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