Che JX - Search Results

1

Alkenyl/thiol-derived metal-organic frameworks (MOFs) by means of postsynthetic modification for effective mercury adsorption.

Liu T, Che JX, Hu YZ, Dong XW, Liu XY, Che CM. Liu T, et al. Among authors: che jx. Chemistry. 2014 Oct 20;20(43):14090-5. doi: 10.1002/chem.201403382. Epub 2014 Sep 10. Chemistry. 2014. PMID: 25210002

2

Integrating docking scores, interaction profiles and molecular descriptors to improve the accuracy of molecular docking: toward the discovery of novel Akt1 inhibitors.

Zhan W, Li D, Che J, Zhang L, Yang B, Hu Y, Liu T, Dong X. Zhan W, et al. Eur J Med Chem. 2014 Mar 21;75:11-20. doi: 10.1016/j.ejmech.2014.01.019. Epub 2014 Jan 22. Eur J Med Chem. 2014. PMID: 24508830

3

Compartmentalization of Incompatible Polymers within Metal-Organic Frameworks towards Homogenization of Heterogeneous Hybrid Catalysts for Tandem Reactions.

Zhao JH, Yang Y, Che JX, Zuo J, Li XH, Hu YZ, Dong XW, Gao L, Liu XY. Zhao JH, et al. Among authors: che jx. Chemistry. 2018 Jul 11;24(39):9903-9909. doi: 10.1002/chem.201801416. Epub 2018 Jun 19. Chemistry. 2018. PMID: 29714823

4

Ligand-based pharmacophore model for the discovery of novel CXCR2 antagonists as anti-cancer metastatic agents.

Che J, Wang Z, Sheng H, Huang F, Dong X, Hu Y, Xie X, Hu Y. Che J, et al. R Soc Open Sci. 2018 Jul 4;5(7):180176. doi: 10.1098/rsos.180176. eCollection 2018 Jul. R Soc Open Sci. 2018. PMID: 30109074 Free PMC article.

5

Covalent docking modelling-based discovery of tripeptidyl epoxyketone proteasome inhibitors composed of aliphatic-heterocycles.

Dong XW, Zhang JK, Xu L, Che JX, Cheng G, Hu XB, Sheng L, Gao AH, Li J, Liu T, Hu YZ, Zhou YB. Dong XW, et al. Among authors: che jx. Eur J Med Chem. 2019 Feb 15;164:602-614. doi: 10.1016/j.ejmech.2018.12.064. Epub 2018 Dec 26. Eur J Med Chem. 2019. PMID: 30639896

6

Phenotypic Screening-Based Identification of 3,4-Disubstituted Piperidine Derivatives as Macrophage M2 Polarization Modulators: An Opportunity for Treating Multiple Sclerosis.

Weng Q, Che J, Zhang Z, Zheng J, Zhan W, Lin S, Tian T, Wang J, Gai R, Hu Y, Yang B, He Q, Dong X. Weng Q, et al. J Med Chem. 2019 Apr 11;62(7):3268-3285. doi: 10.1021/acs.jmedchem.8b01635. Epub 2019 Mar 22. J Med Chem. 2019. PMID: 30856328

7

Visible-light-mediated guest trapping in a photosensitizing porous coordination network: metal-free C-C bond-forming modification of metal-organic frameworks for aqueous-phase herbicide adsorption.

Yang Y, Che J, Wang B, Wu Y, Chen B, Gao L, Dong X, Zhao J. Yang Y, et al. Chem Commun (Camb). 2019 May 10;55(37):5383-5386. doi: 10.1039/c9cc01371g. Epub 2019 Apr 17. Chem Commun (Camb). 2019. PMID: 30994647

8

GSH Activated Biotin-tagged Near-Infrared Probe for Efficient Cancer Imaging.

Guo R, Huang F, Zhang B, Yan Y, Che J, Jin Y, Zhuang Y, Dong R, Li Y, Tan B, Song R, Hu Y, Dong X, Li X, Lin N. Guo R, et al. Theranostics. 2019 May 26;9(12):3515-3525. doi: 10.7150/thno.32742. eCollection 2019. Theranostics. 2019. PMID: 31281494 Free PMC article.

9

Discovery of 3,4,6-Trisubstituted Piperidine Derivatives as Orally Active, Low hERG Blocking Akt Inhibitors via Conformational Restriction and Structure-Based Design.

Dong X, Zhan W, Zhao M, Che J, Dai X, Wu Y, Xu L, Zhou Y, Zhao Y, Tian T, Cheng G, Jin Z, Li J, Shao Y, He Q, Yang B, Weng Q, Hu Y. Dong X, et al. J Med Chem. 2019 Aug 8;62(15):7264-7288. doi: 10.1021/acs.jmedchem.9b00891. Epub 2019 Jul 24. J Med Chem. 2019. PMID: 31298542

10

Discovery of pyrazole-thiophene derivatives as highly Potent, orally active Akt inhibitors.

Zhan W, Che J, Xu L, Wu Y, Hu X, Zhou Y, Cheng G, Hu Y, Dong X, Li J. Zhan W, et al. Eur J Med Chem. 2019 Oct 15;180:72-85. doi: 10.1016/j.ejmech.2019.07.017. Epub 2019 Jul 7. Eur J Med Chem. 2019. PMID: 31301565

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