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A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics.
Cell. 2014 Sep 11;158(6):1402-1414. doi: 10.1016/j.cell.2014.08.032.
Cell. 2014.
PMID: 25215495
Free PMC article.
Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters.
Cimermancic P, Medema MH, Claesen J, Kurita K, Wieland Brown LC, Mavrommatis K, Pati A, Godfrey PA, Koehrsen M, Clardy J, Birren BW, Takano E, Sali A, Linington RG, Fischbach MA.
Cimermancic P, et al. Among authors: wieland brown lc.
Cell. 2014 Jul 17;158(2):412-421. doi: 10.1016/j.cell.2014.06.034.
Cell. 2014.
PMID: 25036635
Free PMC article.
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Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin.
Wieland Brown LC, Acker MG, Clardy J, Walsh CT, Fischbach MA.
Wieland Brown LC, et al.
Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2549-53. doi: 10.1073/pnas.0900008106. Epub 2009 Feb 5.
Proc Natl Acad Sci U S A. 2009.
PMID: 19196969
Free PMC article.
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Production of α-galactosylceramide by a prominent member of the human gut microbiota.
Wieland Brown LC, Penaranda C, Kashyap PC, Williams BB, Clardy J, Kronenberg M, Sonnenburg JL, Comstock LE, Bluestone JA, Fischbach MA.
Wieland Brown LC, et al.
PLoS Biol. 2013 Jul;11(7):e1001610. doi: 10.1371/journal.pbio.1001610. Epub 2013 Jul 16.
PLoS Biol. 2013.
PMID: 23874157
Free PMC article.
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