Sánchez-Céspedes M - Search Results

1

Modeling lung cancer evolution and preclinical response by orthotopic mouse allografts.

Ambrogio C, Carmona FJ, Vidal A, Falcone M, Nieto P, Romero OA, Puertas S, Vizoso M, Nadal E, Poggio T, Sánchez-Céspedes M, Esteller M, Mulero F, Voena C, Chiarle R, Barbacid M, Santamaría D, Villanueva A. Ambrogio C, et al. Cancer Res. 2014 Nov 1;74(21):5978-88. doi: 10.1158/0008-5472.CAN-14-1606. Epub 2014 Sep 12. Cancer Res. 2014. PMID: 25217522

2

Genetic and epigenetic screening for gene alterations of the chromatin-remodeling factor, SMARCA4/BRG1, in lung tumors.

Medina PP, Carretero J, Fraga MF, Esteller M, Sidransky D, Sanchez-Cespedes M. Medina PP, et al. Genes Chromosomes Cancer. 2004 Oct;41(2):170-7. doi: 10.1002/gcc.20068. Genes Chromosomes Cancer. 2004. PMID: 15287030

3

Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma.

Ambrogio C, Gómez-López G, Falcone M, Vidal A, Nadal E, Crosetto N, Blasco RB, Fernández-Marcos PJ, Sánchez-Céspedes M, Ren X, Wang Z, Ding K, Hidalgo M, Serrano M, Villanueva A, Santamaría D, Barbacid M. Ambrogio C, et al. Nat Med. 2016 Mar;22(3):270-7. doi: 10.1038/nm.4041. Epub 2016 Feb 8. Nat Med. 2016. PMID: 26855149

4

Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung.

Sanchez-Cespedes M, Parrella P, Esteller M, Nomoto S, Trink B, Engles JM, Westra WH, Herman JG, Sidransky D. Sanchez-Cespedes M, et al. Cancer Res. 2002 Jul 1;62(13):3659-62. Cancer Res. 2002. PMID: 12097271

5

Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors.

Paz MF, Avila S, Fraga MF, Pollan M, Capella G, Peinado MA, Sanchez-Cespedes M, Herman JG, Esteller M. Paz MF, et al. Cancer Res. 2002 Aug 1;62(15):4519-24. Cancer Res. 2002. PMID: 12154064

6

Wnt signaling promoter hypermethylation distinguishes lung primary adenocarcinomas from colorectal metastasis to the lung.

Tang M, Torres-Lanzas J, Lopez-Rios F, Esteller M, Sanchez-Cespedes M. Tang M, et al. Int J Cancer. 2006 Dec 1;119(11):2603-6. doi: 10.1002/ijc.22211. Int J Cancer. 2006. PMID: 16991125

7

Therapeutic effect of γ-secretase inhibition in KrasG12V-driven non-small cell lung carcinoma by derepression of DUSP1 and inhibition of ERK.

Maraver A, Fernández-Marcos PJ, Herranz D, Muñoz-Martin M, Gomez-Lopez G, Cañamero M, Mulero F, Megías D, Sanchez-Carbayo M, Shen J, Sanchez-Cespedes M, Palomero T, Ferrando A, Serrano M. Maraver A, et al. Cancer Cell. 2012 Aug 14;22(2):222-34. doi: 10.1016/j.ccr.2012.06.014. Cancer Cell. 2012. PMID: 22897852 Free PMC article.

8

Genetic unmasking of an epigenetically silenced microRNA in human cancer cells.

Lujambio A, Ropero S, Ballestar E, Fraga MF, Cerrato C, Setién F, Casado S, Suarez-Gauthier A, Sanchez-Cespedes M, Git A, Spiteri I, Das PP, Caldas C, Miska E, Esteller M. Lujambio A, et al. Cancer Res. 2007 Feb 15;67(4):1424-9. doi: 10.1158/0008-5472.CAN-06-4218. Cancer Res. 2007. PMID: 17308079

9

CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas.

Paz MF, Yaya-Tur R, Rojas-Marcos I, Reynes G, Pollan M, Aguirre-Cruz L, García-Lopez JL, Piquer J, Safont MJ, Balaña C, Sanchez-Cespedes M, García-Villanueva M, Arribas L, Esteller M. Paz MF, et al. Clin Cancer Res. 2004 Aug 1;10(15):4933-8. doi: 10.1158/1078-0432.CCR-04-0392. Clin Cancer Res. 2004. PMID: 15297393

10

CpG island promoter hypermethylation of the Ras-effector gene NORE1A occurs in the context of a wild-type K-ras in lung cancer.

Irimia M, Fraga MF, Sanchez-Cespedes M, Esteller M. Irimia M, et al. Oncogene. 2004 Nov 11;23(53):8695-9. doi: 10.1038/sj.onc.1207914. Oncogene. 2004. PMID: 15378027

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