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Unique functional and structural properties of the LRRK2 protein ATP-binding pocket.
Liu Z, Galemmo RA Jr, Fraser KB, Moehle MS, Sen S, Volpicelli-Daley LA, DeLucas LJ, Ross LJ, Valiyaveettil J, Moukha-Chafiq O, Pathak AK, Ananthan S, Kezar H, White EL, Gupta V, Maddry JA, Suto MJ, West AB. Liu Z, et al. Among authors: fraser kb. J Biol Chem. 2014 Nov 21;289(47):32937-51. doi: 10.1074/jbc.M114.602318. Epub 2014 Sep 16. J Biol Chem. 2014. PMID: 25228699 Free PMC article.
LRRK2 secretion in exosomes is regulated by 14-3-3.
Fraser KB, Moehle MS, Daher JP, Webber PJ, Williams JY, Stewart CA, Yacoubian TA, Cowell RM, Dokland T, Ye T, Chen D, Siegal GP, Galemmo RA, Tsika E, Moore DJ, Standaert DG, Kojima K, Mobley JA, West AB. Fraser KB, et al. Hum Mol Genet. 2013 Dec 15;22(24):4988-5000. doi: 10.1093/hmg/ddt346. Epub 2013 Jul 25. Hum Mol Genet. 2013. PMID: 23886663 Free PMC article.
LRRK2 levels in immune cells are increased in Parkinson's disease.
Cook DA, Kannarkat GT, Cintron AF, Butkovich LM, Fraser KB, Chang J, Grigoryan N, Factor SA, West AB, Boss JM, Tansey MG. Cook DA, et al. Among authors: fraser kb. NPJ Parkinsons Dis. 2017 Mar 28;3:11. doi: 10.1038/s41531-017-0010-8. eCollection 2017. NPJ Parkinsons Dis. 2017. PMID: 28649611 Free PMC article.
Corrigendum to "α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration" [Neurobiol. Dis., Volume 105 (2017) Article 84, 98].
Abdelmotilib H, Maltbie T, Delic V, Liu Z, Hu X, Fraser KB, Moehle MS, Stoyka L, Anabtawi N, Krendelchtchikova V, Volpicelli-Daley LA, West A. Abdelmotilib H, et al. Among authors: fraser kb. Neurobiol Dis. 2021 Nov;159:105506. doi: 10.1016/j.nbd.2021.105506. Epub 2021 Sep 24. Neurobiol Dis. 2021. PMID: 34565675 Free article. No abstract available.
Glucocerebrosidase Activity is not Associated with Parkinson's Disease Risk or Severity.
Omer N, Giladi N, Gurevich T, Bar-Shira A, Gana-Weisz M, Glinka T, Goldstein O, Kestenbaum M, Cedarbaum JM, Mabrouk OS, Fraser KB, Shirvan JC, Orr-Urtreger A, Mirelman A, Thaler A. Omer N, et al. Among authors: fraser kb. Mov Disord. 2022 Jan;37(1):190-195. doi: 10.1002/mds.28792. Epub 2021 Sep 22. Mov Disord. 2022. PMID: 34550621 Free PMC article.
80 results