LaBarbera DV - Search Results

1

An improved high yield total synthesis and cytotoxicity study of the marine alkaloid neoamphimedine: an ATP-competitive inhibitor of topoisomerase IIα and potent anticancer agent.

Li L, Abraham AD, Zhou Q, Ali H, O'Brien JV, Hamill BD, Arcaroli JJ, Messersmith WA, LaBarbera DV. Li L, et al. Among authors: labarbera dv. Mar Drugs. 2014 Sep 19;12(9):4833-50. doi: 10.3390/md12094833. Mar Drugs. 2014. PMID: 25244109 Free PMC article.

2

3D models of epithelial-mesenchymal transition in breast cancer metastasis: high-throughput screening assay development, validation, and pilot screen.

Li Q, Chen C, Kapadia A, Zhou Q, Harper MK, Schaack J, LaBarbera DV. Li Q, et al. Among authors: labarbera dv. J Biomol Screen. 2011 Feb;16(2):141-54. doi: 10.1177/1087057110392995. J Biomol Screen. 2011. PMID: 21297102

3

Neoamphimedine circumvents metnase-enhanced DNA topoisomerase IIα activity through ATP-competitive inhibition.

Ponder J, Yoo BH, Abraham AD, Li Q, Ashley AK, Amerin CL, Zhou Q, Reid BG, Reigan P, Hromas R, Nickoloff JA, LaBarbera DV. Ponder J, et al. Among authors: labarbera dv. Mar Drugs. 2011;9(11):2397-2408. doi: 10.3390/md9112397. Epub 2011 Nov 18. Mar Drugs. 2011. PMID: 22163192 Free PMC article.

4

Design of an amide N-glycoside derivative of β-glucogallin: a stable, potent, and specific inhibitor of aldose reductase.

Li L, Chang KC, Zhou Y, Shieh B, Ponder J, Abraham AD, Ali H, Snow A, Petrash JM, LaBarbera DV. Li L, et al. Among authors: labarbera dv. J Med Chem. 2014 Jan 9;57(1):71-7. doi: 10.1021/jm401311d. Epub 2013 Dec 23. J Med Chem. 2014. PMID: 24341381 Free PMC article.

5

Live multicellular tumor spheroid models for high-content imaging and screening in cancer drug discovery.

Reid BG, Jerjian T, Patel P, Zhou Q, Yoo BH, Kabos P, Sartorius CA, Labarbera DV. Reid BG, et al. Among authors: labarbera dv. Curr Chem Genom Transl Med. 2014 Feb 7;8(Suppl 1):27-35. doi: 10.2174/2213988501408010027. eCollection 2014. Curr Chem Genom Transl Med. 2014. PMID: 24596682 Free PMC article.

6

High-throughput imaging: Focusing in on drug discovery in 3D.

Li L, Zhou Q, Voss TC, Quick KL, LaBarbera DV. Li L, et al. Among authors: labarbera dv. Methods. 2016 Mar 1;96:97-102. doi: 10.1016/j.ymeth.2015.11.013. Epub 2015 Nov 21. Methods. 2016. PMID: 26608110 Free PMC article. Review.

7

Novel Microtubule-Targeting 7-Deazahypoxanthines Derived from Marine Alkaloid Rigidins with Potent in Vitro and in Vivo Anticancer Activities.

Medellin DC, Zhou Q, Scott R, Hill RM, Frail SK, Dasari R, Ontiveros SJ, Pelly SC, van Otterlo WA, Betancourt T, Shuster CB, Hamel E, Bai R, LaBarbera DV, Rogelj S, Frolova LV, Kornienko A. Medellin DC, et al. Among authors: labarbera dv. J Med Chem. 2016 Jan 14;59(1):480-5. doi: 10.1021/acs.jmedchem.5b01426. Epub 2015 Dec 17. J Med Chem. 2016. PMID: 26641132 Free PMC article.

8

Topoisomerase IIα mediates TCF-dependent epithelial-mesenchymal transition in colon cancer.

Zhou Q, Abraham AD, Li L, Babalmorad A, Bagby S, Arcaroli JJ, Hansen RJ, Valeriote FA, Gustafson DL, Schaack J, Messersmith WA, LaBarbera DV. Zhou Q, et al. Among authors: labarbera dv. Oncogene. 2016 Sep 22;35(38):4990-9. doi: 10.1038/onc.2016.29. Epub 2016 Mar 7. Oncogene. 2016. PMID: 26947016 Free PMC article.

9

Characterization of Emodin as a Therapeutic Agent for Diabetic Cataract.

Chang KC, Li L, Sanborn TM, Shieh B, Lenhart P, Ammar D, LaBarbera DV, Petrash JM. Chang KC, et al. Among authors: labarbera dv. J Nat Prod. 2016 May 27;79(5):1439-44. doi: 10.1021/acs.jnatprod.6b00185. Epub 2016 May 3. J Nat Prod. 2016. PMID: 27140653 Free PMC article.

10

Larrea tridentata: A novel source for anti-parasitic agents active against Entamoeba histolytica, Giardia lamblia and Naegleria fowleri.

Bashyal B, Li L, Bains T, Debnath A, LaBarbera DV. Bashyal B, et al. Among authors: labarbera dv. PLoS Negl Trop Dis. 2017 Aug 9;11(8):e0005832. doi: 10.1371/journal.pntd.0005832. eCollection 2017 Aug. PLoS Negl Trop Dis. 2017. PMID: 28793307 Free PMC article.

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