Li L - Search Results

1

An improved high yield total synthesis and cytotoxicity study of the marine alkaloid neoamphimedine: an ATP-competitive inhibitor of topoisomerase IIα and potent anticancer agent.

Li L, Abraham AD, Zhou Q, Ali H, O'Brien JV, Hamill BD, Arcaroli JJ, Messersmith WA, LaBarbera DV. Li L, et al. Mar Drugs. 2014 Sep 19;12(9):4833-50. doi: 10.3390/md12094833. Mar Drugs. 2014. PMID: 25244109 Free PMC article.

2

Topoisomerase IIα mediates TCF-dependent epithelial-mesenchymal transition in colon cancer.

Zhou Q, Abraham AD, Li L, Babalmorad A, Bagby S, Arcaroli JJ, Hansen RJ, Valeriote FA, Gustafson DL, Schaack J, Messersmith WA, LaBarbera DV. Zhou Q, et al. Among authors: li l. Oncogene. 2016 Sep 22;35(38):4990-9. doi: 10.1038/onc.2016.29. Epub 2016 Mar 7. Oncogene. 2016. PMID: 26947016 Free PMC article.

3

Design of an amide N-glycoside derivative of β-glucogallin: a stable, potent, and specific inhibitor of aldose reductase.

Li L, Chang KC, Zhou Y, Shieh B, Ponder J, Abraham AD, Ali H, Snow A, Petrash JM, LaBarbera DV. Li L, et al. J Med Chem. 2014 Jan 9;57(1):71-7. doi: 10.1021/jm401311d. Epub 2013 Dec 23. J Med Chem. 2014. PMID: 24341381 Free PMC article.

4

Drug Design Targeting T-Cell Factor-Driven Epithelial-Mesenchymal Transition as a Therapeutic Strategy for Colorectal Cancer.

Abraham AD, Esquer H, Zhou Q, Tomlinson N, Hamill BD, Abbott JM, Li L, Pike LA, Rinaldetti S, Ramirez DA, Lunghofer PJ, Gomez JD, Schaack J, Nemkov T, D'Alessandro A, Hansen KC, Gustafson DL, Messersmith WA, LaBarbera DV. Abraham AD, et al. Among authors: li l. J Med Chem. 2019 Nov 27;62(22):10182-10203. doi: 10.1021/acs.jmedchem.9b01065. Epub 2019 Nov 18. J Med Chem. 2019. PMID: 31675229 Free PMC article.

5

High-throughput imaging: Focusing in on drug discovery in 3D.

Li L, Zhou Q, Voss TC, Quick KL, LaBarbera DV. Li L, et al. Methods. 2016 Mar 1;96:97-102. doi: 10.1016/j.ymeth.2015.11.013. Epub 2015 Nov 21. Methods. 2016. PMID: 26608110 Free PMC article. Review.

6

Identification of small molecule inhibitors of the Chikungunya virus nsP1 RNA capping enzyme.

Feibelman KM, Fuller BP, Li L, LaBarbera DV, Geiss BJ. Feibelman KM, et al. Among authors: li l. Antiviral Res. 2018 Jun;154:124-131. doi: 10.1016/j.antiviral.2018.03.013. Epub 2018 Apr 20. Antiviral Res. 2018. PMID: 29680670 Free PMC article.

7

Characterization of Emodin as a Therapeutic Agent for Diabetic Cataract.

Chang KC, Li L, Sanborn TM, Shieh B, Lenhart P, Ammar D, LaBarbera DV, Petrash JM. Chang KC, et al. Among authors: li l. J Nat Prod. 2016 May 27;79(5):1439-44. doi: 10.1021/acs.jnatprod.6b00185. Epub 2016 May 3. J Nat Prod. 2016. PMID: 27140653 Free PMC article.

8

Larrea tridentata: A novel source for anti-parasitic agents active against Entamoeba histolytica, Giardia lamblia and Naegleria fowleri.

Bashyal B, Li L, Bains T, Debnath A, LaBarbera DV. Bashyal B, et al. Among authors: li l. PLoS Negl Trop Dis. 2017 Aug 9;11(8):e0005832. doi: 10.1371/journal.pntd.0005832. eCollection 2017 Aug. PLoS Negl Trop Dis. 2017. PMID: 28793307 Free PMC article.

9

Targeting HIV-1 Protease Autoprocessing for High-throughput Drug Discovery and Drug Resistance Assessment.

Huang L, Li L, Tien C, LaBarbera DV, Chen C. Huang L, et al. Among authors: li l. Sci Rep. 2019 Jan 22;9(1):301. doi: 10.1038/s41598-018-36730-4. Sci Rep. 2019. PMID: 30670786 Free PMC article.

10

High Throughput Screen Identifies the DNMT1 (DNA Methyltransferase-1) Inhibitor, 5-Azacytidine, as a Potent Inducer of PTEN (Phosphatase and Tensin Homolog): Central Role for PTEN in 5-Azacytidine Protection Against Pathological Vascular Remodeling.

Strand KA, Lu S, Mutryn MF, Li L, Zhou Q, Enyart BT, Jolly AJ, Dubner AM, Moulton KS, Nemenoff RA, Koch KA, LaBarbera DV, Weiser-Evans MCM. Strand KA, et al. Among authors: li l. Arterioscler Thromb Vasc Biol. 2020 Aug;40(8):1854-1869. doi: 10.1161/ATVBAHA.120.314458. Epub 2020 Jun 25. Arterioscler Thromb Vasc Biol. 2020. PMID: 32580634 Free PMC article.

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