Luo J - Search Results

1

Selective targeting of KRAS-mutant cells by miR-126 through repression of multiple genes essential for the survival of KRAS-mutant cells.

Hara T, Jones MF, Subramanian M, Li XL, Ou O, Zhu Y, Yang Y, Wakefield LM, Hussain SP, Gaedcke J, Ried T, Luo J, Caplen NJ, Lal A. Hara T, et al. Among authors: luo j. Oncotarget. 2014 Sep 15;5(17):7635-50. doi: 10.18632/oncotarget.2284. Oncotarget. 2014. PMID: 25245095 Free PMC article.

2

Evolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cells.

Weng MT, Lee JH, Wei SC, Li Q, Shahamatdar S, Hsu D, Schetter AJ, Swatkoski S, Mannan P, Garfield S, Gucek M, Kim MK, Annunziata CM, Creighton CJ, Emanuele MJ, Harris CC, Sheu JC, Giaccone G, Luo J. Weng MT, et al. Among authors: luo j. Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):E3659-67. doi: 10.1073/pnas.1207673110. Epub 2012 Dec 10. Proc Natl Acad Sci U S A. 2012. PMID: 23236152 Free PMC article.

3

A p21-ZEB1 complex inhibits epithelial-mesenchymal transition through the microRNA 183-96-182 cluster.

Li XL, Hara T, Choi Y, Subramanian M, Francis P, Bilke S, Walker RL, Pineda M, Zhu Y, Yang Y, Luo J, Wakefield LM, Brabletz T, Park BH, Sharma S, Chowdhury D, Meltzer PS, Lal A. Li XL, et al. Among authors: luo j. Mol Cell Biol. 2014 Feb;34(3):533-50. doi: 10.1128/MCB.01043-13. Epub 2013 Nov 25. Mol Cell Biol. 2014. PMID: 24277930 Free PMC article.

4

A high-throughput assay for small molecule destabilizers of the KRAS oncoprotein.

Carver J, Dexheimer TS, Hsu D, Weng MT, Smith JL, Guha R, Jadhav A, Simeonov A, Luo J. Carver J, et al. Among authors: luo j. PLoS One. 2014 Aug 5;9(8):e103836. doi: 10.1371/journal.pone.0103836. eCollection 2014. PLoS One. 2014. PMID: 25093678 Free PMC article.

5

Development of siRNA payloads to target KRAS-mutant cancer.

Yuan TL, Fellmann C, Lee CS, Ritchie CD, Thapar V, Lee LC, Hsu DJ, Grace D, Carver JO, Zuber J, Luo J, McCormick F, Lowe SW. Yuan TL, et al. Among authors: luo j. Cancer Discov. 2014 Oct;4(10):1182-1197. doi: 10.1158/2159-8290.CD-13-0900. Epub 2014 Aug 6. Cancer Discov. 2014. PMID: 25100204 Free PMC article.

6

High mesothelin expression in advanced lung adenocarcinoma is associated with KRAS mutations and a poor prognosis.

Thomas A, Chen Y, Steinberg SM, Luo J, Pack S, Raffeld M, Abdullaev Z, Alewine C, Rajan A, Giaccone G, Pastan I, Miettinen M, Hassan R. Thomas A, et al. Among authors: luo j. Oncotarget. 2015 May 10;6(13):11694-703. doi: 10.18632/oncotarget.3429. Oncotarget. 2015. PMID: 26028668 Free PMC article. Clinical Trial.

7

A synthetic-lethality RNAi screen reveals an ERK-mTOR co-targeting pro-apoptotic switch in PIK3CA+ oral cancers.

Yamaguchi K, Iglesias-Bartolomé R, Wang Z, Callejas-Valera JL, Amornphimoltham P, Molinolo AA, Cohen EE, Califano JA, Lippman SM, Luo J, Gutkind JS. Yamaguchi K, et al. Among authors: luo j. Oncotarget. 2016 Mar 8;7(10):10696-709. doi: 10.18632/oncotarget.7372. Oncotarget. 2016. PMID: 26882569 Free PMC article.

8

MAP kinase and autophagy pathways cooperate to maintain RAS mutant cancer cell survival.

Lee CS, Lee LC, Yuan TL, Chakka S, Fellmann C, Lowe SW, Caplen NJ, McCormick F, Luo J. Lee CS, et al. Among authors: luo j. Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4508-4517. doi: 10.1073/pnas.1817494116. Epub 2019 Feb 1. Proc Natl Acad Sci U S A. 2019. PMID: 30709910 Free PMC article.

9

KRAS mutation in pancreatic cancer.

Luo J. Luo J. Semin Oncol. 2021 Feb;48(1):10-18. doi: 10.1053/j.seminoncol.2021.02.003. Epub 2021 Feb 23. Semin Oncol. 2021. PMID: 33676749 Free PMC article. Review.

10

Protein phosphatase 6 activates NF-κB to confer sensitivity to MAPK pathway inhibitors in KRAS- and BRAF-mutant cancer cells.

Zhang H, Read A, Cataisson C, Yang HH, Lee WC, Turk BE, Yuspa SH, Luo J. Zhang H, et al. Among authors: luo j. Sci Signal. 2024 May 14;17(836):eadd5073. doi: 10.1126/scisignal.add5073. Epub 2024 May 14. Sci Signal. 2024. PMID: 38743809 Free PMC article.

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