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Evidence that formulations of the selective MAO-B inhibitor, selegiline, which bypass first-pass metabolism, also inhibit MAO-A in the human brain.
Fowler JS, Logan J, Volkow ND, Shumay E, McCall-Perez F, Jayne M, Wang GJ, Alexoff DL, Apelskog-Torres K, Hubbard B, Carter P, King P, Fahn S, Gilmor M, Telang F, Shea C, Xu Y, Muench L. Fowler JS, et al. Neuropsychopharmacology. 2015 Feb;40(3):650-7. doi: 10.1038/npp.2014.214. Epub 2014 Sep 24. Neuropsychopharmacology. 2015. PMID: 25249059 Free PMC article. Clinical Trial.
PET imaging of monoamine oxidase B in peripheral organs in humans.
Fowler JS, Logan J, Wang GJ, Volkow ND, Zhu W, Franceschi D, Pappas N, Ferrieri R, Shea C, Garza V, Xu Y, MacGregor RR, Schlyer D, Gatley SJ, Ding YS, Alexoff D. Fowler JS, et al. J Nucl Med. 2002 Oct;43(10):1331-8. J Nucl Med. 2002. PMID: 12368371 Free article.
The MAO-A genotype does not modulate resting brain metabolism in adults.
Alia-Klein N, Kriplani A, Pradhan K, Ma JY, Logan J, Williams B, Craig IW, Telang F, Tomasi D, Goldstein RZ, Wang GJ, Volkow ND, Fowler JS. Alia-Klein N, et al. Among authors: fowler js. Psychiatry Res. 2008 Oct 30;164(1):73-6. doi: 10.1016/j.pscychresns.2007.12.010. Epub 2008 Aug 15. Psychiatry Res. 2008. PMID: 18706791 Free PMC article.
Fast uptake and long-lasting binding of methamphetamine in the human brain: comparison with cocaine.
Fowler JS, Volkow ND, Logan J, Alexoff D, Telang F, Wang GJ, Wong C, Ma Y, Kriplani A, Pradhan K, Schlyer D, Jayne M, Hubbard B, Carter P, Warner D, King P, Shea C, Xu Y, Muench L, Apelskog K. Fowler JS, et al. Neuroimage. 2008 Dec;43(4):756-63. doi: 10.1016/j.neuroimage.2008.07.020. Epub 2008 Jul 22. Neuroimage. 2008. PMID: 18708148 Free PMC article. Clinical Trial.
Reversible inhibitors of monoamine oxidase-A (RIMAs): robust, reversible inhibition of human brain MAO-A by CX157.
Fowler JS, Logan J, Azzaro AJ, Fielding RM, Zhu W, Poshusta AK, Burch D, Brand B, Free J, Asgharnejad M, Wang GJ, Telang F, Hubbard B, Jayne M, King P, Carter P, Carter S, Xu Y, Shea C, Muench L, Alexoff D, Shumay E, Schueller M, Warner D, Apelskog-Torres K. Fowler JS, et al. Neuropsychopharmacology. 2010 Feb;35(3):623-31. doi: 10.1038/npp.2009.167. Epub 2009 Nov 4. Neuropsychopharmacology. 2010. PMID: 19890267 Free PMC article.
470 results