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Connecting gene expression data from connectivity map and in silico target predictions for small molecule mechanism-of-action analysis.
Ravindranath AC, Perualila-Tan N, Kasim A, Drakakis G, Liggi S, Brewerton SC, Mason D, Bodkin MJ, Evans DA, Bhagwat A, Talloen W, Göhlmann HW, Shkedy Z, Bender A; QSTAR Consortium. Ravindranath AC, et al. Among authors: talloen w. Mol Biosyst. 2015 Jan;11(1):86-96. doi: 10.1039/c4mb00328d. Epub 2014 Sep 25. Mol Biosyst. 2015. PMID: 25254964
A joint modeling approach for uncovering associations between gene expression, bioactivity and chemical structure in early drug discovery to guide lead selection and genomic biomarker development.
Perualila-Tan N, Kasim A, Talloen W, Verbist B, Göhlmann HW; QSTAR Consortium; Shkedy Z. Perualila-Tan N, et al. Among authors: talloen w. Stat Appl Genet Mol Biol. 2016 Aug 1;15(4):291-304. doi: 10.1515/sagmb-2014-0086. Stat Appl Genet Mol Biol. 2016. PMID: 27269248
Gene filtering in the analysis of Illumina microarray experiments.
Forcheh AC, Verbeke G, Kasim A, Lin D, Shkedy Z, Talloen W, Göhlmann HW, Clement L. Forcheh AC, et al. Among authors: talloen w. Stat Appl Genet Mol Biol. 2012 Jan 6;11(2):/j/sagmb.2012.11.issue-2/1544-6115.1710/1544-6115.1710.xml. doi: 10.2202/1544-6115.1710. Stat Appl Genet Mol Biol. 2012. PMID: 22499694
Comparison of methods for the selection of genomic biomarkers.
Lin D, Tilahun A, Abrahantes JC, Shkedy Z, Molenberghs G, Gohlmann HW, Talloen W, Bijnens L. Lin D, et al. Among authors: talloen w. Int J Data Min Bioinform. 2013;8(1):24-41. doi: 10.1504/ijdmb.2013.054691. Int J Data Min Bioinform. 2013. PMID: 23865163
Translation of disease associated gene signatures across tissues.
Kasim A, Shkedy Z, Lin D, Van Sanden S, Abrahantes JC, Göhlmann HW, Bijnens L, Yekutieli D, Camilleri M, Aerssens J, Talloen W. Kasim A, et al. Among authors: talloen w. Int J Data Min Bioinform. 2015;11(3):301-13. doi: 10.1504/ijdmb.2015.067321. Int J Data Min Bioinform. 2015. PMID: 26333264
The high-level similarity of some disparate gene expression measures.
Raghavan N, De Bondt AM, Talloen W, Moechars D, Göhlmann HW, Amaratunga D. Raghavan N, et al. Among authors: talloen w. Bioinformatics. 2007 Nov 15;23(22):3032-8. doi: 10.1093/bioinformatics/btm448. Epub 2007 Sep 24. Bioinformatics. 2007. PMID: 17893087
59 results