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Page 1
Proteolytic control of TGF-β co-receptor activity by BMP-1/tolloid-like proteases revealed by quantitative iTRAQ proteomics.
Delolme F, Anastasi C, Alcaraz LB, Mendoza V, Vadon-Le Goff S, Talantikite M, Capomaccio R, Mevaere J, Fortin L, Mazzocut D, Damour O, Zanella-Cléon I, Hulmes DJ, Overall CM, Valcourt U, Lopez-Casillas F, Moali C. Delolme F, et al. Among authors: alcaraz lb. Cell Mol Life Sci. 2015 Mar;72(5):1009-27. doi: 10.1007/s00018-014-1733-x. Epub 2014 Sep 27. Cell Mol Life Sci. 2015. PMID: 25260970 Free PMC article.
SPARC in cancer-associated fibroblasts is an independent poor prognostic factor in non-metastatic triple-negative breast cancer and exhibits pro-tumor activity.
Alcaraz LB, Mallavialle A, Mollevi C, Boissière-Michot F, Mansouri H, Simony-Lafontaine J, Laurent-Matha V, Chardès T, Jacot W, Turtoi A, Roger P, Guiu S, Liaudet-Coopman E. Alcaraz LB, et al. Int J Cancer. 2023 Mar 15;152(6):1243-1258. doi: 10.1002/ijc.34345. Epub 2022 Nov 30. Int J Cancer. 2023. PMID: 36346290 Free PMC article.
Tenascin-X: beyond the architectural function.
Valcourt U, Alcaraz LB, Exposito JY, Lethias C, Bartholin L. Valcourt U, et al. Among authors: alcaraz lb. Cell Adh Migr. 2015;9(1-2):154-65. doi: 10.4161/19336918.2014.994893. Cell Adh Migr. 2015. PMID: 25793578 Free PMC article. Review.
TIF1γ Suppresses Tumor Progression by Regulating Mitotic Checkpoints and Chromosomal Stability.
Pommier RM, Gout J, Vincent DF, Alcaraz LB, Chuvin N, Arfi V, Martel S, Kaniewski B, Devailly G, Fourel G, Bernard P, Moyret-Lalle C, Ansieau S, Puisieux A, Valcourt U, Sentis S, Bartholin L. Pommier RM, et al. Among authors: alcaraz lb. Cancer Res. 2015 Oct 15;75(20):4335-50. doi: 10.1158/0008-5472.CAN-14-3426. Epub 2015 Aug 17. Cancer Res. 2015. PMID: 26282171
Acinar-to-Ductal Metaplasia Induced by Transforming Growth Factor Beta Facilitates KRASG12D-driven Pancreatic Tumorigenesis.
Chuvin N, Vincent DF, Pommier RM, Alcaraz LB, Gout J, Caligaris C, Yacoub K, Cardot V, Roger E, Kaniewski B, Martel S, Cintas C, Goddard-Léon S, Colombe A, Valantin J, Gadot N, Servoz E, Morton J, Goddard I, Couvelard A, Rebours V, Guillermet J, Sansom OJ, Treilleux I, Valcourt U, Sentis S, Dubus P, Bartholin L. Chuvin N, et al. Among authors: alcaraz lb. Cell Mol Gastroenterol Hepatol. 2017 May 31;4(2):263-282. doi: 10.1016/j.jcmgh.2017.05.005. eCollection 2017 Sep. Cell Mol Gastroenterol Hepatol. 2017. PMID: 28752115 Free PMC article.
BMP-1 disrupts cell adhesion and enhances TGF-β activation through cleavage of the matricellular protein thrombospondin-1.
Anastasi C, Rousselle P, Talantikite M, Tessier A, Cluzel C, Bachmann A, Mariano N, Dussoyer M, Alcaraz LB, Fortin L, Aubert A, Delolme F, El Kholti N, Armengaud J, Fournié P, Auxenfans C, Valcourt U, Goff SV, Moali C. Anastasi C, et al. Among authors: alcaraz lb. Sci Signal. 2020 Jul 7;13(639):eaba3880. doi: 10.1126/scisignal.aba3880. Sci Signal. 2020. PMID: 32636307
A 9-kDa matricellular SPARC fragment released by cathepsin D exhibits pro-tumor activity in the triple-negative breast cancer microenvironment.
Alcaraz LB, Mallavialle A, David T, Derocq D, Delolme F, Dieryckx C, Mollevi C, Boissière-Michot F, Simony-Lafontaine J, Du Manoir S, Huesgen PF, Overall CM, Tartare-Deckert S, Jacot W, Chardès T, Guiu S, Roger P, Reinheckel T, Moali C, Liaudet-Coopman E. Alcaraz LB, et al. Theranostics. 2021 Apr 15;11(13):6173-6192. doi: 10.7150/thno.58254. eCollection 2021. Theranostics. 2021. PMID: 33995652 Free PMC article.
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