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Increased Rab35 expression is a potential biomarker and implicated in the pathogenesis of Parkinson's disease.
Chiu CC, Yeh TH, Lai SC, Weng YH, Huang YC, Cheng YC, Chen RS, Huang YZ, Hung J, Chen CC, Lin WY, Chang HC, Chen YJ, Chen CL, Chen HY, Lin YW, Wu-Chou YH, Wang HL, Lu CS. Chiu CC, et al. Among authors: chen cc, chen rs, chen yj, chen hy, chen cl. Oncotarget. 2016 Aug 23;7(34):54215-54227. doi: 10.18632/oncotarget.11090. Oncotarget. 2016. PMID: 27509057 Free PMC article.
PARK14 PLA2G6 mutants are defective in preventing rotenone-induced mitochondrial dysfunction, ROS generation and activation of mitochondrial apoptotic pathway.
Chiu CC, Yeh TH, Lu CS, Huang YC, Cheng YC, Huang YZ, Weng YH, Liu YC, Lai SC, Chen YL, Chen YJ, Chen CL, Chen HY, Lin YW, Wang HL. Chiu CC, et al. Among authors: chen yj, chen hy, chen yl, chen cl. Oncotarget. 2017 Sep 15;8(45):79046-79060. doi: 10.18632/oncotarget.20893. eCollection 2017 Oct 3. Oncotarget. 2017. PMID: 29108286 Free PMC article.
PARK14 (D331Y) PLA2G6 Causes Early-Onset Degeneration of Substantia Nigra Dopaminergic Neurons by Inducing Mitochondrial Dysfunction, ER Stress, Mitophagy Impairment and Transcriptional Dysregulation in a Knockin Mouse Model.
Chiu CC, Lu CS, Weng YH, Chen YL, Huang YZ, Chen RS, Cheng YC, Huang YC, Liu YC, Lai SC, Lin KJ, Lin YW, Chen YJ, Chen CL, Yeh TH, Wang HL. Chiu CC, et al. Among authors: chen rs, chen yj, chen yl, chen cl. Mol Neurobiol. 2019 Jun;56(6):3835-3853. doi: 10.1007/s12035-018-1118-5. Epub 2018 Aug 8. Mol Neurobiol. 2019. PMID: 30088174
Functional variant rs17525453 within RAB35 gene promoter is possibly associated with increased risk of Parkinson's disease in Taiwanese population.
Wang HL, Yeh TH, Huang YZ, Weng YH, Chen RS, Lu CS, Wei KC, Liu YC, Chen YL, Chen CL, Chen YJ, Lin YW, Hsu CC, Chiu CH, Chiu CC. Wang HL, et al. Among authors: chen rs, chen yj, chen yl, chen cl. Neurobiol Aging. 2021 Nov;107:189-196. doi: 10.1016/j.neurobiolaging.2021.06.011. Epub 2021 Jun 19. Neurobiol Aging. 2021. PMID: 34275689
Tract-specific white matter hyperintensities and neuropsychiatric syndromes: a multicentre memory clinic study.
Kan CN, Coenen M, Xu X, Hilal S, Barkhof F, Benke T, Dal-Bianco P, DeCarli C, Duering M, Enzinger C, Exalto LG, Fletcher EF, Hofer E, Koek HL, Kuijf HJ, Maillard PM, Moonen JEF, Papma JM, Pijnenburg YAL, Schmidt R, Steketee RME, van den Berg E, van der Flier WM, Venketasubramanian N, Vernooij MW, Wolters FJ, Biessels GJ, Chen CL, Biesbroek JM, Tan CH; Alzheimer’s Disease Neuroimaging Initiative. Kan CN, et al. Among authors: chen cl. J Neurol Neurosurg Psychiatry. 2025 Jan 6:jnnp-2024-334264. doi: 10.1136/jnnp-2024-334264. Online ahead of print. J Neurol Neurosurg Psychiatry. 2025. PMID: 39761997
4,559 results