Lechtenberg BC - Search Results

1

Development and structural analysis of a nanomolar cyclic peptide antagonist for the EphA4 receptor.

Lamberto I, Lechtenberg BC, Olson EJ, Mace PD, Dawson PE, Riedl SJ, Pasquale EB. Lamberto I, et al. Among authors: lechtenberg bc. ACS Chem Biol. 2014 Dec 19;9(12):2787-95. doi: 10.1021/cb500677x. Epub 2014 Oct 14. ACS Chem Biol. 2014. PMID: 25268696 Free PMC article.

2

Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling.

Roy MJ, Surudoi MG, Kropp A, Hou J, Dai W, Hardy JM, Liang LY, Cotton TR, Lechtenberg BC, Dite TA, Ma X, Daly RJ, Patel O, Lucet IS. Roy MJ, et al. Among authors: lechtenberg bc. Nat Commun. 2023 Jun 19;14(1):3542. doi: 10.1038/s41467-023-38869-9. Nat Commun. 2023. PMID: 37336884 Free PMC article.

3

Just how big is the ubiquitin system?

Lechtenberg BC, Komander D. Lechtenberg BC, et al. Nat Struct Mol Biol. 2024 Feb;31(2):210-213. doi: 10.1038/s41594-023-01208-z. Nat Struct Mol Biol. 2024. PMID: 38347149 No abstract available.

4

Structural mechanisms in NLR inflammasome signaling.

Lechtenberg BC, Mace PD, Riedl SJ. Lechtenberg BC, et al. Curr Opin Struct Biol. 2014 Dec;29:17-25. doi: 10.1016/j.sbi.2014.08.011. Epub 2014 Sep 15. Curr Opin Struct Biol. 2014. PMID: 25201319 Free PMC article. Review.

5

The elastase-PK101 structure: mechanism of an ultrasensitive activity-based probe revealed.

Lechtenberg BC, Kasperkiewicz P, Robinson H, Drag M, Riedl SJ. Lechtenberg BC, et al. ACS Chem Biol. 2015 Apr 17;10(4):945-51. doi: 10.1021/cb500909n. Epub 2015 Jan 22. ACS Chem Biol. 2015. PMID: 25581168

6

Rosetta Stone of NLR Innate Immunity.

Lechtenberg BC, Riedl SJ. Lechtenberg BC, et al. Trends Biochem Sci. 2016 Jan;41(1):6-8. doi: 10.1016/j.tibs.2015.11.008. Epub 2015 Nov 26. Trends Biochem Sci. 2016. PMID: 26631419 Free PMC article.

7

Structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation.

Lechtenberg BC, Rajput A, Sanishvili R, Dobaczewska MK, Ware CF, Mace PD, Riedl SJ. Lechtenberg BC, et al. Nature. 2016 Jan 28;529(7587):546-50. doi: 10.1038/nature16511. Epub 2016 Jan 20. Nature. 2016. PMID: 26789245 Free PMC article.

8

Modifications of a Nanomolar Cyclic Peptide Antagonist for the EphA4 Receptor To Achieve High Plasma Stability.

Olson EJ, Lechtenberg BC, Zhao C, Rubio de la Torre E, Lamberto I, Riedl SJ, Dawson PE, Pasquale EB. Olson EJ, et al. Among authors: lechtenberg bc. ACS Med Chem Lett. 2016 Jun 25;7(9):841-6. doi: 10.1021/acsmedchemlett.6b00132. eCollection 2016 Sep 8. ACS Med Chem Lett. 2016. PMID: 27660688 Free PMC article.

9

Structure-Guided Strategy for the Development of Potent Bivalent ERK Inhibitors.

Lechtenberg BC, Mace PD, Sessions EH, Williamson R, Stalder R, Wallez Y, Roth GP, Riedl SJ, Pasquale EB. Lechtenberg BC, et al. ACS Med Chem Lett. 2017 Jun 12;8(7):726-731. doi: 10.1021/acsmedchemlett.7b00127. eCollection 2017 Jul 13. ACS Med Chem Lett. 2017. PMID: 28740606 Free PMC article.

10

Engineering nanomolar peptide ligands that differentially modulate EphA2 receptor signaling.

Gomez-Soler M, Petersen Gehring M, Lechtenberg BC, Zapata-Mercado E, Hristova K, Pasquale EB. Gomez-Soler M, et al. Among authors: lechtenberg bc. J Biol Chem. 2019 May 31;294(22):8791-8805. doi: 10.1074/jbc.RA119.008213. Epub 2019 Apr 23. J Biol Chem. 2019. PMID: 31015204 Free PMC article.

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