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Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-β-catenin-mediated intestinal tumor growth and regeneration.
Phesse TJ, Buchert M, Stuart E, Flanagan DJ, Faux M, Afshar-Sterle S, Walker F, Zhang HH, Nowell CJ, Jorissen R, Tan CW, Hirokawa Y, Eissmann MF, Poh AR, Malaterre J, Pearson HB, Kirsch DG, Provero P, Poli V, Ramsay RG, Sieber O, Burgess AW, Huszar D, Vincan E, Ernst M. Phesse TJ, et al. Among authors: eissmann mf. Sci Signal. 2014 Sep 30;7(345):ra92. doi: 10.1126/scisignal.2005411. Sci Signal. 2014. PMID: 25270258 Free article.
Stomach-Specific Activation of Oncogenic KRAS and STAT3-Dependent Inflammation Cooperatively Promote Gastric Tumorigenesis in a Preclinical Model.
Thiem S, Eissmann MF, Elzer J, Jonas A, Putoczki TL, Poh A, Nguyen P, Preaudet A, Flanagan D, Vincan E, Waring P, Buchert M, Jarnicki A, Ernst M. Thiem S, et al. Among authors: eissmann mf. Cancer Res. 2016 Apr 15;76(8):2277-87. doi: 10.1158/0008-5472.CAN-15-3089. Epub 2016 Feb 2. Cancer Res. 2016. PMID: 26837764
IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization.
Eissmann MF, Dijkstra C, Jarnicki A, Phesse T, Brunnberg J, Poh AR, Etemadi N, Tsantikos E, Thiem S, Huntington ND, Hibbs ML, Boussioutas A, Grimbaldeston MA, Buchert M, O'Donoghue RJJ, Masson F, Ernst M. Eissmann MF, et al. Nat Commun. 2019 Jun 21;10(1):2735. doi: 10.1038/s41467-019-10676-1. Nat Commun. 2019. PMID: 31227713 Free PMC article.
Inhibition of the SRC Kinase HCK Impairs STAT3-Dependent Gastric Tumor Growth in Mice.
Poh AR, Dwyer AR, Eissmann MF, Chand AL, Baloyan D, Boon L, Murrey MW, Whitehead L, O'Brien M, Lowell CA, Putoczki TL, Pixley FJ, O'Donoghue RJJ, Ernst M. Poh AR, et al. Among authors: eissmann mf. Cancer Immunol Res. 2020 Apr;8(4):428-435. doi: 10.1158/2326-6066.CIR-19-0623. Epub 2020 Jan 28. Cancer Immunol Res. 2020. PMID: 31992566 Free PMC article.
24 results