Gocheva V - Search Results

1

Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix.

Akkari L, Gocheva V, Kester JC, Hunter KE, Quick ML, Sevenich L, Wang HW, Peters C, Tang LH, Klimstra DS, Reinheckel T, Joyce JA. Akkari L, et al. Among authors: gocheva v. Genes Dev. 2014 Oct 1;28(19):2134-50. doi: 10.1101/gad.249599.114. Genes Dev. 2014. PMID: 25274726 Free PMC article.

2

Distinct roles for cysteine cathepsin genes in multistage tumorigenesis.

Gocheva V, Zeng W, Ke D, Klimstra D, Reinheckel T, Peters C, Hanahan D, Joyce JA. Gocheva V, et al. Genes Dev. 2006 Mar 1;20(5):543-56. doi: 10.1101/gad.1407406. Epub 2006 Feb 15. Genes Dev. 2006. PMID: 16481467 Free PMC article.

3

IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion.

Gocheva V, Wang HW, Gadea BB, Shree T, Hunter KE, Garfall AL, Berman T, Joyce JA. Gocheva V, et al. Genes Dev. 2010 Feb 1;24(3):241-55. doi: 10.1101/gad.1874010. Epub 2010 Jan 15. Genes Dev. 2010. PMID: 20080943 Free PMC article.

4

Deletion of cathepsin H perturbs angiogenic switching, vascularization and growth of tumors in a mouse model of pancreatic islet cell cancer.

Gocheva V, Chen X, Peters C, Reinheckel T, Joyce JA. Gocheva V, et al. Biol Chem. 2010 Aug;391(8):937-45. doi: 10.1515/BC.2010.080. Biol Chem. 2010. PMID: 20731543 Free PMC article.

5

Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer.

Akkari L, Gocheva V, Quick ML, Kester JC, Spencer AK, Garfall AL, Bowman RL, Joyce JA. Akkari L, et al. Among authors: gocheva v. Genes Dev. 2016 Jan 15;30(2):220-32. doi: 10.1101/gad.270439.115. Genes Dev. 2016. PMID: 26773004 Free PMC article.

6

Deficiency of the macrophage growth factor CSF-1 disrupts pancreatic neuroendocrine tumor development.

Pyonteck SM, Gadea BB, Wang HW, Gocheva V, Hunter KE, Tang LH, Joyce JA. Pyonteck SM, et al. Among authors: gocheva v. Oncogene. 2012 Mar 15;31(11):1459-67. doi: 10.1038/onc.2011.337. Epub 2011 Aug 8. Oncogene. 2012. PMID: 21822305

7

Cysteine cathepsins and the cutting edge of cancer invasion.

Gocheva V, Joyce JA. Gocheva V, et al. Cell Cycle. 2007 Jan 1;6(1):60-4. doi: 10.4161/cc.6.1.3669. Epub 2007 Jan 6. Cell Cycle. 2007. PMID: 17245112 Review.

8

Identification and pre-clinical testing of a reversible cathepsin protease inhibitor reveals anti-tumor efficacy in a pancreatic cancer model.

Elie BT, Gocheva V, Shree T, Dalrymple SA, Holsinger LJ, Joyce JA. Elie BT, et al. Among authors: gocheva v. Biochimie. 2010 Nov;92(11):1618-24. doi: 10.1016/j.biochi.2010.04.023. Epub 2010 May 4. Biochimie. 2010. PMID: 20447439 Free PMC article.

9

Proteomic Identification of Cysteine Cathepsin Substrates Shed from the Surface of Cancer Cells.

Sobotič B, Vizovišek M, Vidmar R, Van Damme P, Gocheva V, Joyce JA, Gevaert K, Turk V, Turk B, Fonović M. Sobotič B, et al. Among authors: gocheva v. Mol Cell Proteomics. 2015 Aug;14(8):2213-28. doi: 10.1074/mcp.M114.044628. Epub 2015 Jun 16. Mol Cell Proteomics. 2015. PMID: 26081835 Free PMC article.

10

Legumain is activated in macrophages during pancreatitis.

Edgington-Mitchell LE, Wartmann T, Fleming AK, Gocheva V, van der Linden WA, Withana NP, Verdoes M, Aurelio L, Edgington-Mitchell D, Lieu T, Parker BS, Graham B, Reinheckel T, Furness JB, Joyce JA, Storz P, Halangk W, Bogyo M, Bunnett NW. Edgington-Mitchell LE, et al. Among authors: gocheva v. Am J Physiol Gastrointest Liver Physiol. 2016 Sep 1;311(3):G548-60. doi: 10.1152/ajpgi.00047.2016. Epub 2016 Aug 11. Am J Physiol Gastrointest Liver Physiol. 2016. PMID: 27514475 Free PMC article.

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