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SIRT1 activation by a c-MYC oncogenic network promotes the maintenance and drug resistance of human FLT3-ITD acute myeloid leukemia stem cells.
Li L, Osdal T, Ho Y, Chun S, McDonald T, Agarwal P, Lin A, Chu S, Qi J, Li L, Hsieh YT, Dos Santos C, Yuan H, Ha TQ, Popa M, Hovland R, Bruserud Ø, Gjertsen BT, Kuo YH, Chen W, Lain S, McCormack E, Bhatia R. Li L, et al. Among authors: gjertsen bt. Cell Stem Cell. 2014 Oct 2;15(4):431-446. doi: 10.1016/j.stem.2014.08.001. Cell Stem Cell. 2014. PMID: 25280219 Free PMC article.
In vitro crosstalk between fibroblasts and native human acute myelogenous leukemia (AML) blasts via local cytokine networks results in increased proliferation and decreased apoptosis of AML cells as well as increased levels of proangiogenic Interleukin 8.
Ryningen A, Wergeland L, Glenjen N, Gjertsen BT, Bruserud O. Ryningen A, et al. Among authors: gjertsen bt. Leuk Res. 2005 Feb;29(2):185-96. doi: 10.1016/j.leukres.2004.06.008. Leuk Res. 2005. PMID: 15607368
287 results