Horton JD - Search Results

1

Deletion of ELOVL6 blocks the synthesis of oleic acid but does not prevent the development of fatty liver or insulin resistance.

Moon YA, Ochoa CR, Mitsche MA, Hammer RE, Horton JD. Moon YA, et al. Among authors: horton jd. J Lipid Res. 2014 Dec;55(12):2597-605. doi: 10.1194/jlr.M054353. Epub 2014 Oct 3. J Lipid Res. 2014. PMID: 25281760 Free PMC article.

2

Regulatory effects of n-3 polyunsaturated fatty acids on hepatic LDL uptake in the hamster and rat.

Spady DK, Horton JD, Cuthbert JA. Spady DK, et al. Among authors: horton jd. J Lipid Res. 1995 May;36(5):1009-20. J Lipid Res. 1995. PMID: 7658148 Free article.

3

RAP, a specialized chaperone, prevents ligand-induced ER retention and degradation of LDL receptor-related endocytic receptors.

Willnow TE, Rohlmann A, Horton J, Otani H, Braun JR, Hammer RE, Herz J. Willnow TE, et al. EMBO J. 1996 Jun 3;15(11):2632-9. EMBO J. 1996. PMID: 8654360 Free PMC article.

4

Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a.

Shimano H, Horton JD, Hammer RE, Shimomura I, Brown MS, Goldstein JL. Shimano H, et al. Among authors: horton jd. J Clin Invest. 1996 Oct 1;98(7):1575-84. doi: 10.1172/JCI118951. J Clin Invest. 1996. PMID: 8833906 Free PMC article.

5

Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells.

Shimano H, Horton JD, Shimomura I, Hammer RE, Brown MS, Goldstein JL. Shimano H, et al. Among authors: horton jd. J Clin Invest. 1997 Mar 1;99(5):846-54. doi: 10.1172/JCI119248. J Clin Invest. 1997. PMID: 9062341 Free PMC article.

6

Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene.

Shimano H, Shimomura I, Hammer RE, Herz J, Goldstein JL, Brown MS, Horton JD. Shimano H, et al. Among authors: horton jd. J Clin Invest. 1997 Oct 15;100(8):2115-24. doi: 10.1172/JCI119746. J Clin Invest. 1997. PMID: 9329978 Free PMC article.

7

Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.

Horton JD, Shimomura I, Brown MS, Hammer RE, Goldstein JL, Shimano H. Horton JD, et al. J Clin Invest. 1998 Jun 1;101(11):2331-9. doi: 10.1172/JCI2961. J Clin Invest. 1998. PMID: 9616204 Free PMC article.

8

Blunted feedback suppression of SREBP processing by dietary cholesterol in transgenic mice expressing sterol-resistant SCAP(D443N).

Korn BS, Shimomura I, Bashmakov Y, Hammer RE, Horton JD, Goldstein JL, Brown MS. Korn BS, et al. Among authors: horton jd. J Clin Invest. 1998 Dec 15;102(12):2050-60. doi: 10.1172/JCI5341. J Clin Invest. 1998. PMID: 9854040 Free PMC article.

9

SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation.

Matsuda M, Korn BS, Hammer RE, Moon YA, Komuro R, Horton JD, Goldstein JL, Brown MS, Shimomura I. Matsuda M, et al. Among authors: horton jd. Genes Dev. 2001 May 15;15(10):1206-16. doi: 10.1101/gad.891301. Genes Dev. 2001. PMID: 11358865 Free PMC article.

10

Identification of a mammalian long chain fatty acyl elongase regulated by sterol regulatory element-binding proteins.

Moon YA, Shah NA, Mohapatra S, Warrington JA, Horton JD. Moon YA, et al. Among authors: horton jd. J Biol Chem. 2001 Nov 30;276(48):45358-66. doi: 10.1074/jbc.M108413200. Epub 2001 Sep 20. J Biol Chem. 2001. PMID: 11567032 Free article.

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