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Open label randomized comparison of dihydroartemisinin-piperaquine and artesunate-amodiaquine for the treatment of uncomplicated Plasmodium falciparum malaria in central Vietnam.
Thanh NX, Trung TN, Phong NC, Thien NX, Dai B, Shanks GD, Chavchich M, Edstein MD. Thanh NX, et al. Among authors: chavchich m. Trop Med Int Health. 2009 May;14(5):504-11. doi: 10.1111/j.1365-3156.2009.02269.x. Epub 2009 Mar 19. Trop Med Int Health. 2009. PMID: 19320869 Free article. Clinical Trial.
Pharmacokinetics and ex vivo pharmacodynamic antimalarial activity of dihydroartemisinin-piperaquine in patients with uncomplicated falciparum malaria in Vietnam.
Nguyen DV, Nguyen QP, Nguyen ND, Le TT, Nguyen TD, Dinh DN, Nguyen TX, Bui D, Chavchich M, Edstein MD. Nguyen DV, et al. Among authors: chavchich m. Antimicrob Agents Chemother. 2009 Aug;53(8):3534-7. doi: 10.1128/AAC.01717-08. Epub 2009 Jun 15. Antimicrob Agents Chemother. 2009. PMID: 19528277 Free PMC article. Clinical Trial.
The efficacy and tolerability of artemisinin-piperaquine (Artequick®) versus artesunate-amodiaquine (Coarsucam™) for the treatment of uncomplicated Plasmodium falciparum malaria in south-central Vietnam.
Thanh NX, Trung TN, Phong NC, Quang HH, Dai B, Shanks GD, Chavchich M, Edstein MD. Thanh NX, et al. Among authors: chavchich m. Malar J. 2012 Jun 28;11:217. doi: 10.1186/1475-2875-11-217. Malar J. 2012. PMID: 22741618 Free PMC article. Clinical Trial.
Acyclic nucleoside phosphonates containing a second phosphonate group are potent inhibitors of 6-oxopurine phosphoribosyltransferases and have antimalarial activity.
Keough DT, Špaček P, Hocková D, Tichý T, Vrbková S, Slavětínská L, Janeba Z, Naesens L, Edstein MD, Chavchich M, Wang TH, de Jersey J, Guddat LW. Keough DT, et al. Among authors: chavchich m. J Med Chem. 2013 Mar 28;56(6):2513-26. doi: 10.1021/jm301893b. Epub 2013 Mar 19. J Med Chem. 2013. PMID: 23448281
48 results