Bhattarai D - Search Results

1

Synthesis and in vitro evaluation of the antitubercular and antibacterial activity of novel oxazolidinones bearing octahydrocyclopenta[c]pyrrol-2-yl moieties.

Bhattarai D, Lee JH, Seo SH, Nam G, Choo H, Kang SB, Kwak JH, Oh T, Cho SN, Pae AN, Kim EE, Jeong N, Keum G. Bhattarai D, et al. Chem Pharm Bull (Tokyo). 2014;62(12):1214-24. doi: 10.1248/cpb.c14-00510. Epub 2014 Oct 9. Chem Pharm Bull (Tokyo). 2014. PMID: 25297523 Free article.

2

Synthesis and in vitro antibacterial activity of novel 3-azabicyclo[3.3.0]octanyl oxazolidinones.

Bhattarai D, Lee SH, Seo SH, Nam G, Kang SB, Pae AN, Kim EE, Oh T, Cho SN, Keum G. Bhattarai D, et al. Chem Biol Drug Des. 2012 Sep;80(3):388-97. doi: 10.1111/j.1747-0285.2012.01404.x. Epub 2012 Jun 27. Chem Biol Drug Des. 2012. PMID: 22553981

3

Virtual screening and synthesis of novel antitubercular agents through interaction-based pharmacophore and molecular docking studies.

Bhattarai D, Muddassar M, Jang JW, Hong SK, Kim EE, Oh T, Cho SN, Pae AN, Keum G. Bhattarai D, et al. Curr Comput Aided Drug Des. 2014;10(4):383-92. doi: 10.2174/1573409911666150414150300. Curr Comput Aided Drug Des. 2014. PMID: 25872944

4

Synthesis and biological evaluation of isoxazoline derivatives as potent M₁ muscarinic acetylcholine receptor agonists.

Huang M, Suk DH, Cho NC, Bhattarai D, Kang SB, Kim Y, Pae AN, Rhim H, Keum G. Huang M, et al. Among authors: bhattarai d. Bioorg Med Chem Lett. 2015 Apr 1;25(7):1546-51. doi: 10.1016/j.bmcl.2015.02.012. Epub 2015 Feb 16. Bioorg Med Chem Lett. 2015. PMID: 25765911

5

Macrocyclic Immunoproteasome Inhibitors as a Potential Therapy for Alzheimer's Disease.

Lee MJ, Bhattarai D, Jang H, Baek A, Yeo IJ, Lee S, Miller Z, Lee S, Hong JT, Kim DE, Lee W, Kim KB. Lee MJ, et al. Among authors: bhattarai d. J Med Chem. 2021 Aug 12;64(15):10934-10950. doi: 10.1021/acs.jmedchem.1c00291. Epub 2021 Jul 26. J Med Chem. 2021. PMID: 34309393 Free PMC article.

6

LMP2 Inhibitors as a Potential Treatment for Alzheimer's Disease.

Bhattarai D, Lee MJ, Baek A, Yeo IJ, Miller Z, Baek YM, Lee S, Kim DE, Hong JT, Kim KB. Bhattarai D, et al. J Med Chem. 2020 Apr 9;63(7):3763-3783. doi: 10.1021/acs.jmedchem.0c00416. Epub 2020 Mar 30. J Med Chem. 2020. PMID: 32189500

7

Design, synthesis, and biological evaluation of structurally modified isoindolinone and quinazolinone derivatives as hedgehog pathway inhibitors.

Bhattarai D, Jung JH, Han S, Lee H, Oh SJ, Ko HW, Lee K. Bhattarai D, et al. Eur J Med Chem. 2017 Jan 5;125:1036-1050. doi: 10.1016/j.ejmech.2016.10.040. Epub 2016 Oct 19. Eur J Med Chem. 2017. PMID: 27810591

8

Hypoxia-inducible factor-1 (HIF-1) inhibitors from the last decade (2007 to 2016): A "structure-activity relationship" perspective.

Bhattarai D, Xu X, Lee K. Bhattarai D, et al. Med Res Rev. 2018 Jul;38(4):1404-1442. doi: 10.1002/med.21477. Epub 2017 Dec 26. Med Res Rev. 2018. PMID: 29278273 Review.

9

Development of Novel Epoxyketone-Based Proteasome Inhibitors as a Strategy To Overcome Cancer Resistance to Carfilzomib and Bortezomib.

Lee MJ, Bhattarai D, Yoo J, Miller Z, Park JE, Lee S, Lee W, Driscoll JJ, Kim KB. Lee MJ, et al. Among authors: bhattarai d. J Med Chem. 2019 May 9;62(9):4444-4455. doi: 10.1021/acs.jmedchem.8b01943. Epub 2019 Apr 19. J Med Chem. 2019. PMID: 30964987 Free PMC article.

10

Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development.

Lim S, Cho HY, Kim DG, Roh Y, Son SY, Mushtaq AU, Kim M, Bhattarai D, Sivaraman A, Lee Y, Lee J, Yang WS, Kim HK, Kim MH, Lee K, Jeon YH, Kim S. Lim S, et al. Among authors: bhattarai d. Nat Chem Biol. 2020 Jan;16(1):31-41. doi: 10.1038/s41589-019-0415-2. Epub 2019 Dec 2. Nat Chem Biol. 2020. PMID: 31792442

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