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Small-molecule inhibitors of urea transporters.
Verkman AS, Esteva-Font C, Cil O, Anderson MO, Li F, Li M, Lei T, Ren H, Yang B. Verkman AS, et al. Among authors: cil o. Subcell Biochem. 2014;73:165-77. doi: 10.1007/978-94-017-9343-8_11. Subcell Biochem. 2014. PMID: 25298345 Free PMC article. Review.
Benzopyrimido-pyrrolo-oxazine-dione CFTR inhibitor (R)-BPO-27 for antisecretory therapy of diarrheas caused by bacterial enterotoxins.
Cil O, Phuan PW, Gillespie AM, Lee S, Tradtrantip L, Yin J, Tse M, Zachos NC, Lin R, Donowitz M, Verkman AS. Cil O, et al. FASEB J. 2017 Feb;31(2):751-760. doi: 10.1096/fj.201600891R. Epub 2016 Nov 8. FASEB J. 2017. PMID: 27871064 Free PMC article.
These studies support the potential utility of (R)-BPO-27 for therapy of CFTR-mediated secretory diarrheas.-Cil, O., Phuan, P.-W., Gillespie, A. M., Lee, S., Tradtrantip, L., Yin, J., Tse, M., Zachos, N. ...
These studies support the potential utility of (R)-BPO-27 for therapy of CFTR-mediated secretory diarrheas.-Cil, O., Phuan, P. …
Substituted 2-Acylaminocycloalkylthiophene-3-carboxylic Acid Arylamides as Inhibitors of the Calcium-Activated Chloride Channel Transmembrane Protein 16A (TMEM16A).
Truong EC, Phuan PW, Reggi AL, Ferrera L, Galietta LJV, Levy SE, Moises AC, Cil O, Diez-Cecilia E, Lee S, Verkman AS, Anderson MO. Truong EC, et al. Among authors: cil o. J Med Chem. 2017 Jun 8;60(11):4626-4635. doi: 10.1021/acs.jmedchem.7b00020. Epub 2017 May 24. J Med Chem. 2017. PMID: 28493701 Free PMC article.
53 results