Clark AR - Search Results

1

Role of mitogen-activated protein kinase phosphatase-1 in corticosteroid insensitivity of chronic oxidant lung injury.

Pinart M, Hussain F, Shirali S, Li F, Zhu J, Clark AR, Ammit AJ, Chung KF. Pinart M, et al. Among authors: clark ar. Eur J Pharmacol. 2014 Dec 5;744:108-14. doi: 10.1016/j.ejphar.2014.10.003. Epub 2014 Oct 12. Eur J Pharmacol. 2014. PMID: 25310910 Free PMC article.

2

Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38.

Lasa M, Abraham SM, Boucheron C, Saklatvala J, Clark AR. Lasa M, et al. Among authors: clark ar. Mol Cell Biol. 2002 Nov;22(22):7802-11. doi: 10.1128/MCB.22.22.7802-7811.2002. Mol Cell Biol. 2002. PMID: 12391149 Free PMC article.

3

Crosstalk between glucocorticoids and mitogen-activated protein kinase signalling pathways.

Clark AR, Lasa M. Clark AR, et al. Curr Opin Pharmacol. 2003 Aug;3(4):404-11. doi: 10.1016/s1471-4892(03)00073-0. Curr Opin Pharmacol. 2003. PMID: 12901950 Review.

4

Increased endothelial mitogen-activated protein kinase phosphatase-1 expression suppresses proinflammatory activation at sites that are resistant to atherosclerosis.

Zakkar M, Chaudhury H, Sandvik G, Enesa K, Luong le A, Cuhlmann S, Mason JC, Krams R, Clark AR, Haskard DO, Evans PC. Zakkar M, et al. Among authors: clark ar. Circ Res. 2008 Sep 26;103(7):726-32. doi: 10.1161/CIRCRESAHA.108.183913. Epub 2008 Aug 21. Circ Res. 2008. PMID: 18723442

5

Temporal regulation of cytokine mRNA expression by tristetraprolin: dynamic control by p38 MAPK and MKP-1.

Prabhala P, Bunge K, Rahman MM, Ge Q, Clark AR, Ammit AJ. Prabhala P, et al. Among authors: clark ar. Am J Physiol Lung Cell Mol Physiol. 2015 May 1;308(9):L973-80. doi: 10.1152/ajplung.00219.2014. Epub 2015 Feb 27. Am J Physiol Lung Cell Mol Physiol. 2015. PMID: 25724669 Free article.

6

Basal protein phosphatase 2A activity restrains cytokine expression: role for MAPKs and tristetraprolin.

Rahman MM, Rumzhum NN, Morris JC, Clark AR, Verrills NM, Ammit AJ. Rahman MM, et al. Among authors: clark ar. Sci Rep. 2015 May 18;5:10063. doi: 10.1038/srep10063. Sci Rep. 2015. PMID: 25985190 Free PMC article.

7

Dual-Specificity Phosphatase 1 and Tristetraprolin Cooperate To Regulate Macrophage Responses to Lipopolysaccharide.

Smallie T, Ross EA, Ammit AJ, Cunliffe HE, Tang T, Rosner DR, Ridley ML, Buckley CD, Saklatvala J, Dean JL, Clark AR. Smallie T, et al. Among authors: clark ar. J Immunol. 2015 Jul 1;195(1):277-88. doi: 10.4049/jimmunol.1402830. Epub 2015 May 27. J Immunol. 2015. PMID: 26019272 Free PMC article.

8

Activating protein phosphatase 2A (PP2A) enhances tristetraprolin (TTP) anti-inflammatory function in A549 lung epithelial cells.

Rahman MM, Rumzhum NN, Hansbro PM, Morris JC, Clark AR, Verrills NM, Ammit AJ. Rahman MM, et al. Among authors: clark ar. Cell Signal. 2016 Apr;28(4):325-34. doi: 10.1016/j.cellsig.2016.01.009. Epub 2016 Jan 26. Cell Signal. 2016. PMID: 26820662

9

The phosphorylated form of FTY720 activates PP2A, represses inflammation and is devoid of S1P agonism in A549 lung epithelial cells.

Rahman MM, Prünte L, Lebender LF, Patel BS, Gelissen I, Hansbro PM, Morris JC, Clark AR, Verrills NM, Ammit AJ. Rahman MM, et al. Among authors: clark ar. Sci Rep. 2016 Nov 16;6:37297. doi: 10.1038/srep37297. Sci Rep. 2016. PMID: 27849062 Free PMC article.

10

Targeting PP2A and proteasome activity ameliorates features of allergic airway disease in mice.

Nair PM, Starkey MR, Haw TJ, Liu G, Horvat JC, Morris JC, Verrills NM, Clark AR, Ammit AJ, Hansbro PM. Nair PM, et al. Among authors: clark ar. Allergy. 2017 Dec;72(12):1891-1903. doi: 10.1111/all.13212. Epub 2017 Jun 21. Allergy. 2017. PMID: 28543283

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