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Covariance of charged amino acids at positions 322 and 440 of HIV-1 Env contributes to coreceptor specificity of subtype B viruses, and can be used to improve the performance of V3 sequence-based coreceptor usage prediction algorithms.
Cashin K, Sterjovski J, Harvey KL, Ramsland PA, Churchill MJ, Gorry PR. Cashin K, et al. Among authors: sterjovski j. PLoS One. 2014 Oct 14;9(10):e109771. doi: 10.1371/journal.pone.0109771. eCollection 2014. PLoS One. 2014. PMID: 25313689 Free PMC article.
Tissue-specific sequence alterations in the human immunodeficiency virus type 1 envelope favoring CCR5 usage contribute to persistence of dual-tropic virus in the brain.
Gray L, Roche M, Churchill MJ, Sterjovski J, Ellett A, Poumbourios P, Sherieff S, Wang B, Saksena N, Purcell DF, Wesselingh S, Cunningham AL, Brew BJ, Gabuzda D, Gorry PR. Gray L, et al. Among authors: sterjovski j. J Virol. 2009 Jun;83(11):5430-41. doi: 10.1128/JVI.02648-08. Epub 2009 Mar 25. J Virol. 2009. PMID: 19321618 Free PMC article.
Structure activity relationship of dendrimer microbicides with dual action antiviral activity.
Tyssen D, Henderson SA, Johnson A, Sterjovski J, Moore K, La J, Zanin M, Sonza S, Karellas P, Giannis MP, Krippner G, Wesselingh S, McCarthy T, Gorry PR, Ramsland PA, Cone R, Paull JR, Lewis GR, Tachedjian G. Tyssen D, et al. Among authors: sterjovski j. PLoS One. 2010 Aug 23;5(8):e12309. doi: 10.1371/journal.pone.0012309. PLoS One. 2010. PMID: 20808791 Free PMC article.
HIV-1 escape from the CCR5 antagonist maraviroc associated with an altered and less-efficient mechanism of gp120-CCR5 engagement that attenuates macrophage tropism.
Roche M, Jakobsen MR, Sterjovski J, Ellett A, Posta F, Lee B, Jubb B, Westby M, Lewin SR, Ramsland PA, Churchill MJ, Gorry PR. Roche M, et al. Among authors: sterjovski j. J Virol. 2011 May;85(9):4330-42. doi: 10.1128/JVI.00106-11. Epub 2011 Feb 23. J Virol. 2011. PMID: 21345957 Free PMC article.
32 results