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Discovery of a novel ERK inhibitor with activity in models of acquired resistance to BRAF and MEK inhibitors.
Morris EJ, Jha S, Restaino CR, Dayananth P, Zhu H, Cooper A, Carr D, Deng Y, Jin W, Black S, Long B, Liu J, Dinunzio E, Windsor W, Zhang R, Zhao S, Angagaw MH, Pinheiro EM, Desai J, Xiao L, Shipps G, Hruza A, Wang J, Kelly J, Paliwal S, Gao X, Babu BS, Zhu L, Daublain P, Zhang L, Lutterbach BA, Pelletier MR, Philippar U, Siliphaivanh P, Witter D, Kirschmeier P, Bishop WR, Hicklin D, Gilliland DG, Jayaraman L, Zawel L, Fawell S, Samatar AA. Morris EJ, et al. Among authors: jin w. Cancer Discov. 2013 Jul;3(7):742-50. doi: 10.1158/2159-8290.CD-13-0070. Epub 2013 Apr 24. Cancer Discov. 2013. PMID: 23614898
MK-8353: Discovery of an Orally Bioavailable Dual Mechanism ERK Inhibitor for Oncology.
Boga SB, Deng Y, Zhu L, Nan Y, Cooper AB, Shipps GW Jr, Doll R, Shih NY, Zhu H, Sun R, Wang T, Paliwal S, Tsui HC, Gao X, Yao X, Desai J, Wang J, Alhassan AB, Kelly J, Patel M, Muppalla K, Gudipati S, Zhang LK, Buevich A, Hesk D, Carr D, Dayananth P, Black S, Mei H, Cox K, Sherborne B, Hruza AW, Xiao L, Jin W, Long B, Liu G, Taylor SA, Kirschmeier P, Windsor WT, Bishop R, Samatar AA. Boga SB, et al. Among authors: jin w. ACS Med Chem Lett. 2018 Jun 14;9(7):761-767. doi: 10.1021/acsmedchemlett.8b00220. eCollection 2018 Jul 12. ACS Med Chem Lett. 2018. PMID: 30034615 Free PMC article.
Analysis of the ERK1,2 transcriptome in mammary epithelial cells.
Grill C, Gheyas F, Dayananth P, Jin W, Ding W, Qiu P, Wang L, Doll RJ, English JM. Grill C, et al. Among authors: jin w. Biochem J. 2004 Aug 1;381(Pt 3):635-44. doi: 10.1042/BJ20031688. Biochem J. 2004. PMID: 15109307 Free PMC article.
Priming versus propagating: distinct immune effects of an alpha- versus beta-particle emitting radiopharmaceutical when combined with immune checkpoint inhibition.
Kerr CP, Jin WJ, Liu P, Grudzinski JJ, Ferreira CA, Rojas HC, Oñate AJ, Kwon O, Hyun M, Idrissou MB, Schwartz RW, Vera JM, Clark PA, Takashima M, Erbe AK, Shea AG, Powers M, Pinchuk AN, Massey CF, Choi C, Hernandez R, Bednarz BP, Ong IM, Weichert JP, Morris ZS. Kerr CP, et al. Among authors: jin wj. bioRxiv [Preprint]. 2024 Dec 26:2024.12.26.630430. doi: 10.1101/2024.12.26.630430. bioRxiv. 2024. PMID: 39763914 Free PMC article. Preprint.
5,695 results