Welcker M - Search Results

1

Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities.

Davis RJ, Welcker M, Clurman BE. Davis RJ, et al. Among authors: welcker m. Cancer Cell. 2014 Oct 13;26(4):455-64. doi: 10.1016/j.ccell.2014.09.013. Cancer Cell. 2014. PMID: 25314076 Free PMC article. Review.

2

Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation.

Welcker M, Singer J, Loeb KR, Grim J, Bloecher A, Gurien-West M, Clurman BE, Roberts JM. Welcker M, et al. Mol Cell. 2003 Aug;12(2):381-92. doi: 10.1016/s1097-2765(03)00287-9. Mol Cell. 2003. PMID: 14536078 Free article.

3

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation.

Welcker M, Orian A, Jin J, Grim JE, Harper JW, Eisenman RN, Clurman BE. Welcker M, et al. Proc Natl Acad Sci U S A. 2004 Jun 15;101(24):9085-90. doi: 10.1073/pnas.0402770101. Epub 2004 May 18. Proc Natl Acad Sci U S A. 2004. PMID: 15150404 Free PMC article.

4

A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size.

Welcker M, Orian A, Grim JE, Eisenman RN, Clurman BE. Welcker M, et al. Curr Biol. 2004 Oct 26;14(20):1852-7. doi: 10.1016/j.cub.2004.09.083. Curr Biol. 2004. PMID: 15498494 Free article.

5

The SV40 large T antigen contains a decoy phosphodegron that mediates its interactions with Fbw7/hCdc4.

Welcker M, Clurman BE. Welcker M, et al. J Biol Chem. 2005 Mar 4;280(9):7654-8. doi: 10.1074/jbc.M413377200. Epub 2004 Dec 20. J Biol Chem. 2005. PMID: 15611062 Free article.

6

Ras activity regulates cyclin E degradation by the Fbw7 pathway.

Minella AC, Welcker M, Clurman BE. Minella AC, et al. Among authors: welcker m. Proc Natl Acad Sci U S A. 2005 Jul 5;102(27):9649-54. doi: 10.1073/pnas.0503677102. Epub 2005 Jun 24. Proc Natl Acad Sci U S A. 2005. PMID: 15980150 Free PMC article.

7

Fbw7/hCDC4 dimerization regulates its substrate interactions.

Welcker M, Clurman BE. Welcker M, et al. Cell Div. 2007 Feb 13;2:7. doi: 10.1186/1747-1028-2-7. Cell Div. 2007. PMID: 17298674 Free PMC article.

8

FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation.

Welcker M, Clurman BE. Welcker M, et al. Nat Rev Cancer. 2008 Feb;8(2):83-93. doi: 10.1038/nrc2290. Nat Rev Cancer. 2008. PMID: 18094723 Review.

9

Isoform- and cell cycle-dependent substrate degradation by the Fbw7 ubiquitin ligase.

Grim JE, Gustafson MP, Hirata RK, Hagar AC, Swanger J, Welcker M, Hwang HC, Ericsson J, Russell DW, Clurman BE. Grim JE, et al. Among authors: welcker m. J Cell Biol. 2008 Jun 16;181(6):913-20. doi: 10.1083/jcb.200802076. J Cell Biol. 2008. PMID: 18559665 Free PMC article.

10

Nucleolar targeting of the fbw7 ubiquitin ligase by a pseudosubstrate and glycogen synthase kinase 3.

Welcker M, Larimore EA, Frappier L, Clurman BE. Welcker M, et al. Mol Cell Biol. 2011 Mar;31(6):1214-24. doi: 10.1128/MCB.01347-10. Epub 2011 Jan 10. Mol Cell Biol. 2011. PMID: 21220517 Free PMC article.

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