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SIMPLE is a good idea (and better with context learning).
Xu Z, Asman AJ, Shanahan PL, Abramson RG, Landman BA. Xu Z, et al. Among authors: shanahan pl. Med Image Comput Comput Assist Interv. 2014;17(Pt 1):364-71. doi: 10.1007/978-3-319-10404-1_46. Med Image Comput Comput Assist Interv. 2014. PMID: 25333139 Free PMC article.
Shape-Constrained Multi-Atlas Segmentation of Spleen in CT.
Xu Z, Li B, Panda S, Asman AJ, Merkle KL, Shanahan PL, Abramson RG, Landman BA. Xu Z, et al. Among authors: shanahan pl. Proc SPIE Int Soc Opt Eng. 2014 Mar 21;9034:903446. doi: 10.1117/12.2043079. Proc SPIE Int Soc Opt Eng. 2014. PMID: 24817808 Free PMC article.