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How do we prevent the vulnerable atherosclerotic plaque from rupturing? Insights from in vivo assessments of plaque, vascular remodeling, and local endothelial shear stress.
Andreou I, Antoniadis AP, Shishido K, Papafaklis MI, Koskinas KC, Chatzizisis YS, Coskun AU, Edelman ER, Feldman CL, Stone PH. Andreou I, et al. Among authors: koskinas kc. J Cardiovasc Pharmacol Ther. 2015 May;20(3):261-75. doi: 10.1177/1074248414555005. Epub 2014 Oct 21. J Cardiovasc Pharmacol Ther. 2015. PMID: 25336461 Review.
Augmented expression and activity of extracellular matrix-degrading enzymes in regions of low endothelial shear stress colocalize with coronary atheromata with thin fibrous caps in pigs.
Chatzizisis YS, Baker AB, Sukhova GK, Koskinas KC, Papafaklis MI, Beigel R, Jonas M, Coskun AU, Stone BV, Maynard C, Shi GP, Libby P, Feldman CL, Edelman ER, Stone PH. Chatzizisis YS, et al. Among authors: koskinas kc. Circulation. 2011 Feb 15;123(6):621-30. doi: 10.1161/CIRCULATIONAHA.110.970038. Epub 2011 Jan 31. Circulation. 2011. PMID: 21282495 Free PMC article.
Thin-capped atheromata with reduced collagen content in pigs develop in coronary arterial regions exposed to persistently low endothelial shear stress.
Koskinas KC, Sukhova GK, Baker AB, Papafaklis MI, Chatzizisis YS, Coskun AU, Quillard T, Jonas M, Maynard C, Antoniadis AP, Shi GP, Libby P, Edelman ER, Feldman CL, Stone PH. Koskinas KC, et al. Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1494-504. doi: 10.1161/ATVBAHA.112.300827. Epub 2013 May 2. Arterioscler Thromb Vasc Biol. 2013. PMID: 23640495 Free PMC article.
Natural history of experimental coronary atherosclerosis and vascular remodeling in relation to endothelial shear stress: a serial, in vivo intravascular ultrasound study.
Koskinas KC, Feldman CL, Chatzizisis YS, Coskun AU, Jonas M, Maynard C, Baker AB, Papafaklis MI, Edelman ER, Stone PH. Koskinas KC, et al. Circulation. 2010 May 18;121(19):2092-101. doi: 10.1161/CIRCULATIONAHA.109.901678. Epub 2010 May 3. Circulation. 2010. PMID: 20439786 Free PMC article.
Flow and atherosclerosis in coronary bifurcations.
Giannoglou GD, Antoniadis AP, Koskinas KC, Chatzizisis YS. Giannoglou GD, et al. Among authors: koskinas kc. EuroIntervention. 2010 Dec;6 Suppl J:J16-23. doi: 10.4244/EIJV6SUPJA4. EuroIntervention. 2010. PMID: 21930484 Review.
146 results