Lock RB - Search Results

1

Opposing regulation of BIM and BCL2 controls glucocorticoid-induced apoptosis of pediatric acute lymphoblastic leukemia cells.

Jing D, Bhadri VA, Beck D, Thoms JA, Yakob NA, Wong JW, Knezevic K, Pimanda JE, Lock RB. Jing D, et al. Among authors: lock rb. Blood. 2015 Jan 8;125(2):273-83. doi: 10.1182/blood-2014-05-576470. Epub 2014 Oct 21. Blood. 2015. PMID: 25336632 Free article.

2

High level resistance to glucocorticoids, associated with a dysfunctional glucocorticoid receptor, in childhood acute lymphoblastic leukemia cells selected for methotrexate resistance.

Catts VS, Farnsworth ML, Haber M, Norris MD, Lutze-Mann LH, Lock RB. Catts VS, et al. Among authors: lock rb. Leukemia. 2001 Jun;15(6):929-35. doi: 10.1038/sj.leu.2402128. Leukemia. 2001. PMID: 11417479

3

The nonobese diabetic/severe combined immunodeficient (NOD/SCID) mouse model of childhood acute lymphoblastic leukemia reveals intrinsic differences in biologic characteristics at diagnosis and relapse.

Lock RB, Liem N, Farnsworth ML, Milross CG, Xue C, Tajbakhsh M, Haber M, Norris MD, Marshall GM, Rice AM. Lock RB, et al. Blood. 2002 Jun 1;99(11):4100-8. doi: 10.1182/blood.v99.11.4100. Blood. 2002. PMID: 12010813 Free article.

4

Characterization of childhood acute lymphoblastic leukemia xenograft models for the preclinical evaluation of new therapies.

Liem NL, Papa RA, Milross CG, Schmid MA, Tajbakhsh M, Choi S, Ramirez CD, Rice AM, Haber M, Norris MD, MacKenzie KL, Lock RB. Liem NL, et al. Among authors: lock rb. Blood. 2004 May 15;103(10):3905-14. doi: 10.1182/blood-2003-08-2911. Epub 2004 Feb 5. Blood. 2004. PMID: 14764536 Free article.

5

Dexamethasone resistance in B-cell precursor childhood acute lymphoblastic leukemia occurs downstream of ligand-induced nuclear translocation of the glucocorticoid receptor.

Bachmann PS, Gorman R, Mackenzie KL, Lutze-Mann L, Lock RB. Bachmann PS, et al. Among authors: lock rb. Blood. 2005 Mar 15;105(6):2519-26. doi: 10.1182/blood-2004-05-2023. Epub 2004 Nov 30. Blood. 2005. PMID: 15572593 Free article.

6

Initial testing of the VEGFR inhibitor AZD2171 by the pediatric preclinical testing program.

Maris JM, Courtright J, Houghton PJ, Morton CL, Gorlick R, Kolb EA, Lock R, Tajbakhsh M, Reynolds CP, Keir ST, Wu J, Smith MA. Maris JM, et al. Pediatr Blood Cancer. 2008 Mar;50(3):581-7. doi: 10.1002/pbc.21232. Pediatr Blood Cancer. 2008. PMID: 17457854

7

Divergent mechanisms of glucocorticoid resistance in experimental models of pediatric acute lymphoblastic leukemia.

Bachmann PS, Gorman R, Papa RA, Bardell JE, Ford J, Kees UR, Marshall GM, Lock RB. Bachmann PS, et al. Among authors: lock rb. Cancer Res. 2007 May 1;67(9):4482-90. doi: 10.1158/0008-5472.CAN-06-4244. Cancer Res. 2007. PMID: 17483364

8

Activity of vincristine, L-ASP, and dexamethasone against acute lymphoblastic leukemia is enhanced by the BH3-mimetic ABT-737 in vitro and in vivo.

Kang MH, Kang YH, Szymanska B, Wilczynska-Kalak U, Sheard MA, Harned TM, Lock RB, Reynolds CP. Kang MH, et al. Among authors: lock rb. Blood. 2007 Sep 15;110(6):2057-66. doi: 10.1182/blood-2007-03-080325. Epub 2007 May 29. Blood. 2007. PMID: 17536015 Free article.

9

Initial testing of cisplatin by the pediatric preclinical testing program.

Tajbakhsh M, Houghton PJ, Morton CL, Kolb EA, Gorlick R, Maris JM, Keir ST, Wu J, Reynolds CP, Smith MA, Lock RB. Tajbakhsh M, et al. Among authors: lock rb. Pediatr Blood Cancer. 2008 May;50(5):992-1000. doi: 10.1002/pbc.21263. Pediatr Blood Cancer. 2008. PMID: 17554786 Clinical Trial.

10

Initial testing of dasatinib by the pediatric preclinical testing program.

Kolb EA, Gorlick R, Houghton PJ, Morton CL, Lock RB, Tajbakhsh M, Reynolds CP, Maris JM, Keir ST, Billups CA, Smith MA. Kolb EA, et al. Among authors: lock rb. Pediatr Blood Cancer. 2008 Jun;50(6):1198-206. doi: 10.1002/pbc.21368. Pediatr Blood Cancer. 2008. PMID: 17914733

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