Young SG - Search Results

1

Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs.

Degagné E, Pandurangan A, Bandhuvula P, Kumar A, Eltanawy A, Zhang M, Yoshinaga Y, Nefedov M, de Jong PJ, Fong LG, Young SG, Bittman R, Ahmedi Y, Saba JD. Degagné E, et al. Among authors: young sg. J Clin Invest. 2014 Dec;124(12):5368-84. doi: 10.1172/JCI74188. Epub 2014 Oct 27. J Clin Invest. 2014. PMID: 25347472 Free PMC article.

2

Prelamin A, Zmpste24, misshapen cell nuclei, and progeria--new evidence suggesting that protein farnesylation could be important for disease pathogenesis.

Young SG, Fong LG, Michaelis S. Young SG, et al. J Lipid Res. 2005 Dec;46(12):2531-58. doi: 10.1194/jlr.R500011-JLR200. Epub 2005 Oct 5. J Lipid Res. 2005. PMID: 16207929 Free article. Review.

3

Prelamin A and lamin A appear to be dispensable in the nuclear lamina.

Fong LG, Ng JK, Lammerding J, Vickers TA, Meta M, Coté N, Gavino B, Qiao X, Chang SY, Young SR, Yang SH, Stewart CL, Lee RT, Bennett CF, Bergo MO, Young SG. Fong LG, et al. Among authors: young sr, young sg. J Clin Invest. 2006 Mar;116(3):743-52. doi: 10.1172/JCI27125. J Clin Invest. 2006. PMID: 16511604 Free PMC article.

4

A farnesyltransferase inhibitor improves disease phenotypes in mice with a Hutchinson-Gilford progeria syndrome mutation.

Yang SH, Meta M, Qiao X, Frost D, Bauch J, Coffinier C, Majumdar S, Bergo MO, Young SG, Fong LG. Yang SH, et al. Among authors: young sg. J Clin Invest. 2006 Aug;116(8):2115-21. doi: 10.1172/JCI28968. J Clin Invest. 2006. PMID: 16862216 Free PMC article.

5

Prelamin A farnesylation and progeroid syndromes.

Young SG, Meta M, Yang SH, Fong LG. Young SG, et al. J Biol Chem. 2006 Dec 29;281(52):39741-5. doi: 10.1074/jbc.R600033200. Epub 2006 Nov 7. J Biol Chem. 2006. PMID: 17090536 Free article. Review.

6

Mouse models of the laminopathies.

Stewart CL, Kozlov S, Fong LG, Young SG. Stewart CL, et al. Among authors: young sg. Exp Cell Res. 2007 Jun 10;313(10):2144-56. doi: 10.1016/j.yexcr.2007.03.026. Epub 2007 Mar 31. Exp Cell Res. 2007. PMID: 17493612 Free PMC article. Review.

7

Treatment with a farnesyltransferase inhibitor improves survival in mice with a Hutchinson-Gilford progeria syndrome mutation.

Yang SH, Qiao X, Fong LG, Young SG. Yang SH, et al. Among authors: young sg. Biochim Biophys Acta. 2008 Jan-Feb;1781(1-2):36-9. doi: 10.1016/j.bbalip.2007.11.003. Epub 2007 Nov 26. Biochim Biophys Acta. 2008. PMID: 18082640 Free PMC article.

8

Eliminating the synthesis of mature lamin A reduces disease phenotypes in mice carrying a Hutchinson-Gilford progeria syndrome allele.

Yang SH, Qiao X, Farber E, Chang SY, Fong LG, Young SG. Yang SH, et al. Among authors: young sg. J Biol Chem. 2008 Mar 14;283(11):7094-9. doi: 10.1074/jbc.M708138200. Epub 2008 Jan 4. J Biol Chem. 2008. PMID: 18178963 Free article.

9

PCSK9 function and physiology.

Peterson AS, Fong LG, Young SG. Peterson AS, et al. Among authors: young sg. J Lipid Res. 2008 Jun;49(6):1152-6. doi: 10.1194/jlr.E800008-JLR200. Epub 2008 Mar 28. J Lipid Res. 2008. PMID: 18375913 Free PMC article. No abstract available.

10

Genetic analyses of the role of RCE1 in RAS membrane association and transformation.

Bergo MO, Wahlstrom AM, Fong LG, Young SG. Bergo MO, et al. Among authors: young sg. Methods Enzymol. 2008;438:367-89. doi: 10.1016/S0076-6879(07)38026-9. Methods Enzymol. 2008. PMID: 18413262 Free PMC article. Review.

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