Del Nagro C - Search Results

1

Depletion of the central metabolite NAD leads to oncosis-mediated cell death.

Del Nagro C, Xiao Y, Rangell L, Reichelt M, O'Brien T. Del Nagro C, et al. J Biol Chem. 2014 Dec 19;289(51):35182-92. doi: 10.1074/jbc.M114.580159. Epub 2014 Oct 29. J Biol Chem. 2014. PMID: 25355314 Free PMC article.

2

Dependence of tumor cell lines and patient-derived tumors on the NAD salvage pathway renders them sensitive to NAMPT inhibition with GNE-618.

Xiao Y, Elkins K, Durieux JK, Lee L, Oeh J, Yang LX, Liang X, DelNagro C, Tremayne J, Kwong M, Liederer BM, Jackson PK, Belmont LD, Sampath D, O'Brien T. Xiao Y, et al. Neoplasia. 2013 Oct;15(10):1151-60. doi: 10.1593/neo.131304. Neoplasia. 2013. PMID: 24204194 Free PMC article.

3

Chk1 inhibition in p53-deficient cell lines drives rapid chromosome fragmentation followed by caspase-independent cell death.

Del Nagro CJ, Choi J, Xiao Y, Rangell L, Mohan S, Pandita A, Zha J, Jackson PK, O'Brien T. Del Nagro CJ, et al. Cell Cycle. 2014;13(2):303-14. doi: 10.4161/cc.27055. Epub 2013 Feb 1. Cell Cycle. 2014. PMID: 24247149 Free PMC article.

4

Identification of preferred chemotherapeutics for combining with a CHK1 inhibitor.

Xiao Y, Ramiscal J, Kowanetz K, Del Nagro C, Malek S, Evangelista M, Blackwood E, Jackson PK, O'Brien T. Xiao Y, et al. Among authors: del nagro c. Mol Cancer Ther. 2013 Nov;12(11):2285-95. doi: 10.1158/1535-7163.MCT-13-0404. Epub 2013 Sep 13. Mol Cancer Ther. 2013. PMID: 24038068

5

Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition.

Boudreau A, Purkey HE, Hitz A, Robarge K, Peterson D, Labadie S, Kwong M, Hong R, Gao M, Del Nagro C, Pusapati R, Ma S, Salphati L, Pang J, Zhou A, Lai T, Li Y, Chen Z, Wei B, Yen I, Sideris S, McCleland M, Firestein R, Corson L, Vanderbilt A, Williams S, Daemen A, Belvin M, Eigenbrot C, Jackson PK, Malek S, Hatzivassiliou G, Sampath D, Evangelista M, O'Brien T. Boudreau A, et al. Among authors: del nagro c. Nat Chem Biol. 2016 Oct;12(10):779-86. doi: 10.1038/nchembio.2143. Epub 2016 Aug 1. Nat Chem Biol. 2016. PMID: 27479743

6

Subcutaneous versus intravenous administration of rituximab: pharmacokinetics, CD20 target coverage and B-cell depletion in cynomolgus monkeys.

Mao CP, Brovarney MR, Dabbagh K, Birnböck HF, Richter WF, Del Nagro CJ. Mao CP, et al. Among authors: del nagro cj. PLoS One. 2013 Nov 12;8(11):e80533. doi: 10.1371/journal.pone.0080533. eCollection 2013. PLoS One. 2013. PMID: 24265828 Free PMC article.

7

Development and validation of a multiplex immunoassay for the simultaneous quantification of type-specific IgG antibodies to E6/E7 oncoproteins of HPV16 and HPV18.

Layman H, Rickert KW, Wilson S, Aksyuk AA, Dunty JM, Natrakul D, Swaminathan N, DelNagro CJ. Layman H, et al. PLoS One. 2020 Mar 26;15(3):e0229672. doi: 10.1371/journal.pone.0229672. eCollection 2020. PLoS One. 2020. PMID: 32214362 Free PMC article.

8

Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell-mediated B-cell cytotoxicity.

Mössner E, Brünker P, Moser S, Püntener U, Schmidt C, Herter S, Grau R, Gerdes C, Nopora A, van Puijenbroek E, Ferrara C, Sondermann P, Jäger C, Strein P, Fertig G, Friess T, Schüll C, Bauer S, Dal Porto J, Del Nagro C, Dabbagh K, Dyer MJ, Poppema S, Klein C, Umaña P. Mössner E, et al. Among authors: del nagro c. Blood. 2010 Jun 3;115(22):4393-402. doi: 10.1182/blood-2009-06-225979. Epub 2010 Mar 1. Blood. 2010. PMID: 20194898 Free PMC article.

9

Evaluation of assay interference and interpretation of CXCR4 receptor occupancy results in a preclinical study with MEDI3185, a fully human antibody to CXCR4.

Schwickart M, Chavez C, Henderson S, Vainshtein I, Standifer N, DelNagro C, Mehrzai F, Schneider A, Roskos L, Liang M. Schwickart M, et al. Cytometry B Clin Cytom. 2016 Mar;90(2):209-19. doi: 10.1002/cyto.b.21327. Epub 2015 Dec 15. Cytometry B Clin Cytom. 2016. PMID: 26384735 Free PMC article.

10

Receptor occupancy assessment by flow cytometry as a pharmacodynamic biomarker in biopharmaceutical development.

Liang M, Schwickart M, Schneider AK, Vainshtein I, Del Nagro C, Standifer N, Roskos LK. Liang M, et al. Among authors: del nagro c. Cytometry B Clin Cytom. 2016 Mar;90(2):117-27. doi: 10.1002/cyto.b.21259. Epub 2015 Jul 31. Cytometry B Clin Cytom. 2016. PMID: 26054054 Free PMC article. Review.

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