Hoffman BE - Search Results

1

Ex Vivo Expanded Autologous Polyclonal Regulatory T Cells Suppress Inhibitor Formation in Hemophilia.

Sarkar D, Biswas M, Liao G, Seay HR, Perrin GQ, Markusic DM, Hoffman BE, Brusko TM, Terhorst C, Herzog RW. Sarkar D, et al. Among authors: hoffman be. Mol Ther Methods Clin Dev. 2014 Jul 30;1:14030-. doi: 10.1038/mtm.2014.30. Mol Ther Methods Clin Dev. 2014. PMID: 25364772 Free PMC article.

2

Muscle as a target for supplementary factor IX gene transfer.

Hoffman BE, Dobrzynski E, Wang L, Hirao L, Mingozzi F, Cao O, Herzog RW. Hoffman BE, et al. Hum Gene Ther. 2007 Jul;18(7):603-13. doi: 10.1089/hum.2007.042. Hum Gene Ther. 2007. PMID: 17594244

3

Coaxing the liver into preventing autoimmune disease in the brain.

Hoffman BE, Herzog RW. Hoffman BE, et al. J Clin Invest. 2008 Oct;118(10):3271-3. doi: 10.1172/JCI37079. J Clin Invest. 2008. PMID: 18802483 Free PMC article.

4

Improved induction of immune tolerance to factor IX by hepatic AAV-8 gene transfer.

Cooper M, Nayak S, Hoffman BE, Terhorst C, Cao O, Herzog RW. Cooper M, et al. Among authors: hoffman be. Hum Gene Ther. 2009 Jul;20(7):767-76. doi: 10.1089/hum.2008.161. Hum Gene Ther. 2009. PMID: 19309290 Free PMC article.

5

Hepatic gene transfer as a means of tolerance induction to transgene products.

LoDuca PA, Hoffman BE, Herzog RW. LoDuca PA, et al. Among authors: hoffman be. Curr Gene Ther. 2009 Apr;9(2):104-14. doi: 10.2174/156652309787909490. Curr Gene Ther. 2009. PMID: 19355868 Free PMC article. Review.

6

Impact of the underlying mutation and the route of vector administration on immune responses to factor IX in gene therapy for hemophilia B.

Cao O, Hoffman BE, Moghimi B, Nayak S, Cooper M, Zhou S, Ertl HC, High KA, Herzog RW. Cao O, et al. Among authors: hoffman be. Mol Ther. 2009 Oct;17(10):1733-42. doi: 10.1038/mt.2009.159. Epub 2009 Jul 14. Mol Ther. 2009. PMID: 19603001 Free PMC article.

7

Tolerance induction to cytoplasmic beta-galactosidase by hepatic AAV gene transfer: implications for antigen presentation and immunotoxicity.

Martino AT, Nayak S, Hoffman BE, Cooper M, Liao G, Markusic DM, Byrne BJ, Terhorst C, Herzog RW. Martino AT, et al. Among authors: hoffman be. PLoS One. 2009 Aug 4;4(8):e6376. doi: 10.1371/journal.pone.0006376. PLoS One. 2009. PMID: 19652717 Free PMC article.

8

Oral delivery of bioencapsulated coagulation factor IX prevents inhibitor formation and fatal anaphylaxis in hemophilia B mice.

Verma D, Moghimi B, LoDuca PA, Singh HD, Hoffman BE, Herzog RW, Daniell H. Verma D, et al. Among authors: hoffman be. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):7101-6. doi: 10.1073/pnas.0912181107. Epub 2010 Mar 29. Proc Natl Acad Sci U S A. 2010. PMID: 20351275 Free PMC article.

9

High-efficiency transduction and correction of murine hemophilia B using AAV2 vectors devoid of multiple surface-exposed tyrosines.

Markusic DM, Herzog RW, Aslanidi GV, Hoffman BE, Li B, Li M, Jayandharan GR, Ling C, Zolotukhin I, Ma W, Zolotukhin S, Srivastava A, Zhong L. Markusic DM, et al. Among authors: hoffman be. Mol Ther. 2010 Dec;18(12):2048-56. doi: 10.1038/mt.2010.172. Epub 2010 Aug 24. Mol Ther. 2010. PMID: 20736929 Free PMC article.

10

Nonredundant roles of IL-10 and TGF-β in suppression of immune responses to hepatic AAV-factor IX gene transfer.

Hoffman BE, Martino AT, Sack BK, Cao O, Liao G, Terhorst C, Herzog RW. Hoffman BE, et al. Mol Ther. 2011 Jul;19(7):1263-72. doi: 10.1038/mt.2011.33. Epub 2011 Mar 8. Mol Ther. 2011. PMID: 21386826 Free PMC article.

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