Lee R - Search Results

1

Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis.

Shih DM, Wang Z, Lee R, Meng Y, Che N, Charugundla S, Qi H, Wu J, Pan C, Brown JM, Vallim T, Bennett BJ, Graham M, Hazen SL, Lusis AJ. Shih DM, et al. Among authors: lee r. J Lipid Res. 2015 Jan;56(1):22-37. doi: 10.1194/jlr.M051680. Epub 2014 Nov 6. J Lipid Res. 2015. PMID: 25378658 Free PMC article.

2

Targeted depletion of hepatic ACAT2-driven cholesterol esterification reveals a non-biliary route for fecal neutral sterol loss.

Brown JM, Bell TA 3rd, Alger HM, Sawyer JK, Smith TL, Kelley K, Shah R, Wilson MD, Davis MA, Lee RG, Graham MJ, Crooke RM, Rudel LL. Brown JM, et al. Among authors: lee rg. J Biol Chem. 2008 Apr 18;283(16):10522-34. doi: 10.1074/jbc.M707659200. Epub 2008 Feb 14. J Biol Chem. 2008. PMID: 18281279 Free PMC article.

3

CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance.

Brown JM, Betters JL, Lord C, Ma Y, Han X, Yang K, Alger HM, Melchior J, Sawyer J, Shah R, Wilson MD, Liu X, Graham MJ, Lee R, Crooke R, Shulman GI, Xue B, Shi H, Yu L. Brown JM, et al. Among authors: lee r. J Lipid Res. 2010 Nov;51(11):3306-15. doi: 10.1194/jlr.M010256. Epub 2010 Aug 27. J Lipid Res. 2010. PMID: 20802159 Free PMC article.

4

Antisense oligonucleotide reduction of apoB-ameliorated atherosclerosis in LDL receptor-deficient mice.

Mullick AE, Fu W, Graham MJ, Lee RG, Witchell D, Bell TA, Whipple CP, Crooke RM. Mullick AE, et al. J Lipid Res. 2011 May;52(5):885-96. doi: 10.1194/jlr.M011791. Epub 2011 Feb 22. J Lipid Res. 2011. PMID: 21343632 Free PMC article.

5

Antisense oligonucleotide lowers plasma levels of apolipoprotein (a) and lipoprotein (a) in transgenic mice.

Merki E, Graham M, Taleb A, Leibundgut G, Yang X, Miller ER, Fu W, Mullick AE, Lee R, Willeit P, Crooke RM, Witztum JL, Tsimikas S. Merki E, et al. Among authors: lee r. J Am Coll Cardiol. 2011 Apr 12;57(15):1611-21. doi: 10.1016/j.jacc.2010.10.052. J Am Coll Cardiol. 2011. PMID: 21474042 Free article.

6

CGI-58/ABHD5-derived signaling lipids regulate systemic inflammation and insulin action.

Lord CC, Betters JL, Ivanova PT, Milne SB, Myers DS, Madenspacher J, Thomas G, Chung S, Liu M, Davis MA, Lee RG, Crooke RM, Graham MJ, Parks JS, Brasaemle DL, Fessler MB, Brown HA, Brown JM. Lord CC, et al. Diabetes. 2012 Feb;61(2):355-63. doi: 10.2337/db11-0994. Epub 2012 Jan 6. Diabetes. 2012. PMID: 22228714 Free PMC article.

7

Comparison of the pharmacological profiles of murine antisense oligonucleotides targeting apolipoprotein B and microsomal triglyceride transfer protein.

Lee RG, Fu W, Graham MJ, Mullick AE, Sipe D, Gattis D, Bell TA, Booten S, Crooke RM. Lee RG, et al. J Lipid Res. 2013 Mar;54(3):602-614. doi: 10.1194/jlr.M029215. Epub 2012 Dec 6. J Lipid Res. 2013. PMID: 23220583 Free PMC article.

8

Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation.

Bennett BJ, de Aguiar Vallim TQ, Wang Z, Shih DM, Meng Y, Gregory J, Allayee H, Lee R, Graham M, Crooke R, Edwards PA, Hazen SL, Lusis AJ. Bennett BJ, et al. Among authors: lee r. Cell Metab. 2013 Jan 8;17(1):49-60. doi: 10.1016/j.cmet.2012.12.011. Cell Metab. 2013. PMID: 23312283 Free PMC article.

9

Antisense oligonucleotide inhibition of apolipoprotein C-III reduces plasma triglycerides in rodents, nonhuman primates, and humans.

Graham MJ, Lee RG, Bell TA 3rd, Fu W, Mullick AE, Alexander VJ, Singleton W, Viney N, Geary R, Su J, Baker BF, Burkey J, Crooke ST, Crooke RM. Graham MJ, et al. Among authors: lee rg. Circ Res. 2013 May 24;112(11):1479-90. doi: 10.1161/CIRCRESAHA.111.300367. Epub 2013 Mar 29. Circ Res. 2013. PMID: 23542898 Clinical Trial.

10

Antisense oligonucleotide inhibition of cholesteryl ester transfer protein enhances RCT in hyperlipidemic, CETP transgenic, LDLr-/- mice.

Bell TA 3rd, Graham MJ, Lee RG, Mullick AE, Fu W, Norris D, Crooke RM. Bell TA 3rd, et al. J Lipid Res. 2013 Oct;54(10):2647-57. doi: 10.1194/jlr.M036509. Epub 2013 Jun 25. J Lipid Res. 2013. PMID: 23801661 Free PMC article.

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