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Page 1
Blocking CD40-TRAF6 interactions by small-molecule inhibitor 6860766 ameliorates the complications of diet-induced obesity in mice.
van den Berg SM, Seijkens TT, Kusters PJ, Zarzycka B, Beckers L, den Toom M, Gijbels MJ, Chatzigeorgiou A, Weber C, de Winther MP, Chavakis T, Nicolaes GA, Lutgens E. van den Berg SM, et al. Among authors: den toom m. Int J Obes (Lond). 2015 May;39(5):782-90. doi: 10.1038/ijo.2014.198. Epub 2014 Nov 13. Int J Obes (Lond). 2015. PMID: 25394307
IgG is elevated in obese white adipose tissue but does not induce glucose intolerance via Fcγ-receptor or complement.
van Dam AD, van Beek L, Pronk ACM, van den Berg SM, Van den Bossche J, de Winther MPJ, Koning F, van Kooten C, Rensen PCN, Boon MR, Verbeek JS, van Dijk KW, van Harmelen V. van Dam AD, et al. Among authors: van den berg sm. Int J Obes (Lond). 2018 Feb;42(2):260-269. doi: 10.1038/ijo.2017.209. Epub 2017 Aug 30. Int J Obes (Lond). 2018. PMID: 28852207
Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance.
Chatzigeorgiou A, Seijkens T, Zarzycka B, Engel D, Poggi M, van den Berg S, van den Berg S, Soehnlein O, Winkels H, Beckers L, Lievens D, Driessen A, Kusters P, Biessen E, Garcia-Martin R, Klotzsche-von Ameln A, Gijbels M, Noelle R, Boon L, Hackeng T, Schulte KM, Xu A, Vriend G, Nabuurs S, Chung KJ, Willems van Dijk K, Rensen PC, Gerdes N, de Winther M, Block NL, Schally AV, Weber C, Bornstein SR, Nicolaes G, Chavakis T, Lutgens E. Chatzigeorgiou A, et al. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2686-91. doi: 10.1073/pnas.1400419111. Epub 2014 Feb 3. Proc Natl Acad Sci U S A. 2014. PMID: 24492375 Free PMC article.
Immune Modulation of Brown(ing) Adipose Tissue in Obesity.
van den Berg SM, van Dam AD, Rensen PC, de Winther MP, Lutgens E. van den Berg SM, et al. Among authors: van dam ad. Endocr Rev. 2017 Feb 1;38(1):46-68. doi: 10.1210/er.2016-1066. Endocr Rev. 2017. PMID: 27849358 Review.
Helminth antigens counteract a rapid high-fat diet-induced decrease in adipose tissue eosinophils.
van den Berg SM, van Dam AD, Kusters PJH, Beckers L, den Toom M, van der Velden S, Van den Bossche J, van Die I, Boon MR, Rensen PCN, Lutgens E, de Winther MPJ. van den Berg SM, et al. Among authors: van den bossche j, den toom m, van die i, van der velden s, van dam ad. J Mol Endocrinol. 2017 Oct;59(3):245-255. doi: 10.1530/JME-17-0112. Epub 2017 Jul 10. J Mol Endocrinol. 2017. PMID: 28694301
Salsalate activates brown adipose tissue in mice.
van Dam AD, Nahon KJ, Kooijman S, van den Berg SM, Kanhai AA, Kikuchi T, Heemskerk MM, van Harmelen V, Lombès M, van den Hoek AM, de Winther MP, Lutgens E, Guigas B, Rensen PC, Boon MR. van Dam AD, et al. Among authors: van harmelen v, van den hoek am, van den berg sm. Diabetes. 2015 May;64(5):1544-54. doi: 10.2337/db14-1125. Epub 2014 Dec 4. Diabetes. 2015. PMID: 25475439
BCG lowers plasma cholesterol levels and delays atherosclerotic lesion progression in mice.
van Dam AD, Bekkering S, Crasborn M, van Beek L, van den Berg SM, Vrieling F, Joosten SA, van Harmelen V, de Winther MPJ, Lütjohann D, Lutgens E, Boon MR, Riksen NP, Rensen PCN, Berbée JFP. van Dam AD, et al. Among authors: van harmelen v, van beek l, van den berg sm. Atherosclerosis. 2016 Aug;251:6-14. doi: 10.1016/j.atherosclerosis.2016.05.031. Epub 2016 May 19. Atherosclerosis. 2016. PMID: 27232458 Free article.
Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages.
Van den Bossche J, Baardman J, Otto NA, van der Velden S, Neele AE, van den Berg SM, Luque-Martin R, Chen HJ, Boshuizen MC, Ahmed M, Hoeksema MA, de Vos AF, de Winther MP. Van den Bossche J, et al. Among authors: van der velden s, van den berg sm. Cell Rep. 2016 Oct 11;17(3):684-696. doi: 10.1016/j.celrep.2016.09.008. Cell Rep. 2016. PMID: 27732846 Free article.
High Fat Diet Increases Circulating Endocannabinoids Accompanied by Increased Synthesis Enzymes in Adipose Tissue.
Kuipers EN, Kantae V, Maarse BCE, van den Berg SM, van Eenige R, Nahon KJ, Reifel-Miller A, Coskun T, de Winther MPJ, Lutgens E, Kooijman S, Harms AC, Hankemeier T, van der Stelt M, Rensen PCN, Boon MR. Kuipers EN, et al. Among authors: van den berg sm. Front Physiol. 2019 Jan 10;9:1913. doi: 10.3389/fphys.2018.01913. eCollection 2018. Front Physiol. 2019. PMID: 30687125 Free PMC article.
55 results