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Structure-guided DOT1L probe optimization by label-free ligand displacement.
Yi JS, Federation AJ, Qi J, Dhe-Paganon S, Hadler M, Xu X, St Pierre R, Varca AC, Wu L, Marineau JJ, Smith WB, Souza A, Chory EJ, Armstrong SA, Bradner JE. Yi JS, et al. Among authors: wu l. ACS Chem Biol. 2015 Mar 20;10(3):667-74. doi: 10.1021/cb500796d. Epub 2015 Jan 15. ACS Chem Biol. 2015. PMID: 25397901 Free PMC article.
Leukemia-specific delivery of mutant NOTCH1 targeted therapy.
Roti G, Qi J, Kitara S, Sanchez-Martin M, Saur Conway A, Varca AC, Su A, Wu L, Kung AL, Ferrando AA, Bradner JE, Stegmaier K. Roti G, et al. Among authors: wu l. J Exp Med. 2018 Jan 2;215(1):197-216. doi: 10.1084/jem.20151778. Epub 2017 Nov 20. J Exp Med. 2018. PMID: 29158376 Free PMC article.
BET-inhibition by JQ1 promotes proliferation and self-renewal capacity of hematopoietic stem cells.
Wroblewski M, Scheller-Wendorff M, Udonta F, Bauer R, Schlichting J, Zhao L, Ben Batalla I, Gensch V, Päsler S, Wu L, Wanior M, Taipaleenmäki H, Bolamperti S, Najafova Z, Pantel K, Bokemeyer C, Qi J, Hesse E, Knapp S, Johnsen S, Loges S. Wroblewski M, et al. Among authors: wu l. Haematologica. 2018 Jun;103(6):939-948. doi: 10.3324/haematol.2017.181354. Epub 2018 Mar 22. Haematologica. 2018. PMID: 29567778 Free PMC article.
Bromodomain Inhibition Reveals FGF15/19 As a Target of Epigenetic Regulation and Metabolic Control.
Kozuka C, Efthymiou V, Sales VM, Zhou L, Osataphan S, Yuchi Y, Chimene-Weiss J, Mulla C, Isganaitis E, Desmond J, Sanechika S, Kusuyama J, Goodyear L, Shi X, Gerszten RE, Aguayo-Mazzucato C, Carapeto P, Teixeira SD, Sandoval D, Alonso-Curbelo D, Wu L, Qi J, Patti ME. Kozuka C, et al. Among authors: wu l. Diabetes. 2022 May 1;71(5):1023-1033. doi: 10.2337/db21-0574. Diabetes. 2022. PMID: 35100352 Free PMC article.
Esophageal Hematoma After Severe Vomiting.
Lei J, Wu L. Lei J, et al. Among authors: wu l. Cureus. 2024 Nov 25;16(11):e74392. doi: 10.7759/cureus.74392. eCollection 2024 Nov. Cureus. 2024. PMID: 39723264 Free PMC article.
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