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Transfer of clinically relevant gene expression signatures in breast cancer: from Affymetrix microarray to Illumina RNA-Sequencing technology.
Fumagalli D, Blanchet-Cohen A, Brown D, Desmedt C, Gacquer D, Michiels S, Rothé F, Majjaj S, Salgado R, Larsimont D, Ignatiadis M, Maetens M, Piccart M, Detours V, Sotiriou C, Haibe-Kains B. Fumagalli D, et al. Among authors: brown d. BMC Genomics. 2014 Nov 21;15(1):1008. doi: 10.1186/1471-2164-15-1008. BMC Genomics. 2014. PMID: 25412710 Free PMC article.
Uncovering the genomic heterogeneity of multifocal breast cancer.
Desmedt C, Fumagalli D, Pietri E, Zoppoli G, Brown D, Nik-Zainal S, Gundem G, Rothé F, Majjaj S, Garuti A, Carminati E, Loi S, Van Brussel T, Boeckx B, Maetens M, Mudie L, Vincent D, Kheddoumi N, Serra L, Massa I, Ballestrero A, Amadori D, Salgado R, de Wind A, Lambrechts D, Piccart M, Larsimont D, Campbell PJ, Sotiriou C. Desmedt C, et al. Among authors: brown d. J Pathol. 2015 Aug;236(4):457-66. doi: 10.1002/path.4540. Epub 2015 May 7. J Pathol. 2015. PMID: 25850943 Free PMC article.
Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome.
Fumagalli D, Gacquer D, Rothé F, Lefort A, Libert F, Brown D, Kheddoumi N, Shlien A, Konopka T, Salgado R, Larsimont D, Polyak K, Willard-Gallo K, Desmedt C, Piccart M, Abramowicz M, Campbell PJ, Sotiriou C, Detours V. Fumagalli D, et al. Among authors: brown d. Cell Rep. 2015 Oct 13;13(2):277-89. doi: 10.1016/j.celrep.2015.09.032. Epub 2015 Oct 1. Cell Rep. 2015. PMID: 26440892 Free PMC article.
Genomic Characterization of Primary Invasive Lobular Breast Cancer.
Desmedt C, Zoppoli G, Gundem G, Pruneri G, Larsimont D, Fornili M, Fumagalli D, Brown D, Rothé F, Vincent D, Kheddoumi N, Rouas G, Majjaj S, Brohée S, Van Loo P, Maisonneuve P, Salgado R, Van Brussel T, Lambrechts D, Bose R, Metzger O, Galant C, Bertucci F, Piccart-Gebhart M, Viale G, Biganzoli E, Campbell PJ, Sotiriou C. Desmedt C, et al. Among authors: brown d. J Clin Oncol. 2016 Jun 1;34(16):1872-81. doi: 10.1200/JCO.2015.64.0334. Epub 2016 Feb 29. J Clin Oncol. 2016. PMID: 26926684
Somatic mutation, copy number and transcriptomic profiles of primary and matched metastatic estrogen receptor-positive breast cancers.
Fumagalli D, Wilson TR, Salgado R, Lu X, Yu J, O'Brien C, Walter K, Huw LY, Criscitiello C, Laios I, Jose V, Brown DN, Rothé F, Maetens M, Zardavas D, Savas P, Larsimont D, Piccart-Gebhart MJ, Michiels S, Lackner MR, Sotiriou C, Loi S. Fumagalli D, et al. Among authors: brown dn. Ann Oncol. 2016 Oct;27(10):1860-6. doi: 10.1093/annonc/mdw286. Ann Oncol. 2016. PMID: 27672107 Free article.
HER2-Overexpressing Breast Cancers Amplify FGFR Signaling upon Acquisition of Resistance to Dual Therapeutic Blockade of HER2.
Hanker AB, Garrett JT, Estrada MV, Moore PD, Ericsson PG, Koch JP, Langley E, Singh S, Kim PS, Frampton GM, Sanford E, Owens P, Becker J, Groseclose MR, Castellino S, Joensuu H, Huober J, Brase JC, Majjaj S, Brohée S, Venet D, Brown D, Baselga J, Piccart M, Sotiriou C, Arteaga CL. Hanker AB, et al. Among authors: brown d. Clin Cancer Res. 2017 Aug 1;23(15):4323-4334. doi: 10.1158/1078-0432.CCR-16-2287. Epub 2017 Apr 5. Clin Cancer Res. 2017. PMID: 28381415 Free PMC article.
Phylogenetic analysis of metastatic progression in breast cancer using somatic mutations and copy number aberrations.
Brown D, Smeets D, Székely B, Larsimont D, Szász AM, Adnet PY, Rothé F, Rouas G, Nagy ZI, Faragó Z, Tőkés AM, Dank M, Szentmártoni G, Udvarhelyi N, Zoppoli G, Pusztai L, Piccart M, Kulka J, Lambrechts D, Sotiriou C, Desmedt C. Brown D, et al. Nat Commun. 2017 Apr 20;8:14944. doi: 10.1038/ncomms14944. Nat Commun. 2017. PMID: 28429735 Free PMC article.
Erratum: Phylogenetic analysis of metastatic progression in breast cancer using somatic mutations and copy number aberrations.
Brown D, Smeets D, Székely B, Larsimont D, Szász AM, Adnet PY, Rothé F, Rouas G, Nagy ZI, Faragó Z, Tőkés AM, Dank M, Szentmártoni G, Udvarhelyi N, Zoppoli G, Pusztai L, Piccart M, Kulka J, Lambrechts D, Sotiriou C, Desmedt C. Brown D, et al. Nat Commun. 2017 Jun 6;8:15759. doi: 10.1038/ncomms15759. Nat Commun. 2017. PMID: 28585536 Free PMC article.
The AURORA pilot study for molecular screening of patients with advanced breast cancer-a study of the breast international group.
Maetens M, Brown D, Irrthum A, Aftimos P, Viale G, Loibl S, Laes JF, Campbell PJ, Thompson A, Cortes J, Seiler S, Vinnicombe S, Oliveira M, Rothé F, Bareche Y, Fumagalli D, Zardavas D, Desmedt C, Piccart M, Loi S, Sotiriou C. Maetens M, et al. Among authors: brown d. NPJ Breast Cancer. 2017 Jun 29;3:23. doi: 10.1038/s41523-017-0026-6. eCollection 2017. NPJ Breast Cancer. 2017. PMID: 28685159 Free PMC article.
Genomic hotspots but few recurrent fusion genes in breast cancer.
Fimereli D, Fumagalli D, Brown D, Gacquer D, Rothé F, Salgado R, Larsimont D, Sotiriou C, Detours V. Fimereli D, et al. Among authors: brown d. Genes Chromosomes Cancer. 2018 Jul;57(7):331-338. doi: 10.1002/gcc.22533. Epub 2018 Mar 22. Genes Chromosomes Cancer. 2018. PMID: 29436103
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