The single-stranded DNA-binding factor SUB1/PC4 alleviates replication stress at telomeres and is a vulnerability of ALT cancer cells.
Dubois JC, Bonnell E, Filion A, Frion J, Zimmer S, Riaz Khan M, Teplitz GM, Casimir L, Méthot É, Marois I, Idrissou M, Jacques PÉ, Wellinger RJ, Maréchal A.
Dubois JC, et al. Among authors: marois i.
Proc Natl Acad Sci U S A. 2025 Jan 14;122(2):e2419712122. doi: 10.1073/pnas.2419712122. Epub 2025 Jan 7.
Proc Natl Acad Sci U S A. 2025.
PMID: 39772744