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Leptin improves fatty liver independently of insulin sensitization and appetite suppression in hepatocyte-specific Pten-deficient mice with insulin hypersensitivity.
Yamamoto-Kataoka S, Ebihara K, Aizawa-Abe M, Nishio M, Kusakabe T, Yamamoto Y, Aotani D, Sakai T, Zhao M, Ebihara C, Gumbilai VM, Hosoda K, Suzuki A, Nakao K. Yamamoto-Kataoka S, et al. Among authors: gumbilai vm. Horm Metab Res. 2015 Mar;47(3):168-75. doi: 10.1055/s-0034-1395531. Epub 2014 Nov 21. Horm Metab Res. 2015. PMID: 25415231
Leptin restores the insulinotropic effect of exenatide in a mouse model of type 2 diabetes with increased adiposity induced by streptozotocin and high-fat diet.
Sakai T, Kusakabe T, Ebihara K, Aotani D, Yamamoto-Kataoka S, Zhao M, Gumbilai VM, Ebihara C, Aizawa-Abe M, Yamamoto Y, Noguchi M, Fujikura J, Hosoda K, Inagaki N, Nakao K. Sakai T, et al. Among authors: gumbilai vm. Am J Physiol Endocrinol Metab. 2014 Oct 15;307(8):E712-9. doi: 10.1152/ajpendo.00272.2014. Epub 2014 Aug 26. Am J Physiol Endocrinol Metab. 2014. PMID: 25159327 Free article.