Yang Y - Search Results

1

FRET-based trilateration of probes bound within functional ryanodine receptors.

Svensson B, Oda T, Nitu FR, Yang Y, Cornea I, Chen-Izu Y, Fessenden JD, Bers DM, Thomas DD, Cornea RL. Svensson B, et al. Among authors: yang y. Biophys J. 2014 Nov 4;107(9):2037-48. doi: 10.1016/j.bpj.2014.09.029. Biophys J. 2014. PMID: 25418089 Free PMC article.

2

Kinetics of FKBP12.6 binding to ryanodine receptors in permeabilized cardiac myocytes and effects on Ca sparks.

Guo T, Cornea RL, Huke S, Camors E, Yang Y, Picht E, Fruen BR, Bers DM. Guo T, et al. Among authors: yang y. Circ Res. 2010 Jun 11;106(11):1743-52. doi: 10.1161/CIRCRESAHA.110.219816. Epub 2010 Apr 29. Circ Res. 2010. PMID: 20431056 Free PMC article.

3

FRET detection of calmodulin binding to the cardiac RyR2 calcium release channel.

Guo T, Fruen BR, Nitu FR, Nguyen TD, Yang Y, Cornea RL, Bers DM. Guo T, et al. Among authors: yang y. Biophys J. 2011 Nov 2;101(9):2170-7. doi: 10.1016/j.bpj.2011.09.030. Epub 2011 Nov 1. Biophys J. 2011. PMID: 22067155 Free PMC article.

4

In cardiomyocytes, binding of unzipping peptide activates ryanodine receptor 2 and reciprocally inhibits calmodulin binding.

Oda T, Yang Y, Nitu FR, Svensson B, Lu X, Fruen BR, Cornea RL, Bers DM. Oda T, et al. Among authors: yang y. Circ Res. 2013 Feb 1;112(3):487-97. doi: 10.1161/CIRCRESAHA.111.300290. Epub 2012 Dec 11. Circ Res. 2013. PMID: 23233753 Free PMC article.

5

Cardiac myocyte Z-line calmodulin is mainly RyR2-bound, and reduction is arrhythmogenic and occurs in heart failure.

Yang Y, Guo T, Oda T, Chakraborty A, Chen L, Uchinoumi H, Knowlton AA, Fruen BR, Cornea RL, Meissner G, Bers DM. Yang Y, et al. Circ Res. 2014 Jan 17;114(2):295-306. doi: 10.1161/CIRCRESAHA.114.302857. Epub 2013 Nov 1. Circ Res. 2014. PMID: 24186966 Free PMC article.

6

Divergent regulation of ryanodine receptor 2 calcium release channels by arrhythmogenic human calmodulin missense mutants.

Hwang HS, Nitu FR, Yang Y, Walweel K, Pereira L, Johnson CN, Faggioni M, Chazin WJ, Laver D, George AL Jr, Cornea RL, Bers DM, Knollmann BC. Hwang HS, et al. Among authors: yang y. Circ Res. 2014 Mar 28;114(7):1114-24. doi: 10.1161/CIRCRESAHA.114.303391. Epub 2014 Feb 21. Circ Res. 2014. PMID: 24563457 Free PMC article.

7

Oxidation of ryanodine receptor (RyR) and calmodulin enhance Ca release and pathologically alter, RyR structure and calmodulin affinity.

Oda T, Yang Y, Uchinoumi H, Thomas DD, Chen-Izu Y, Kato T, Yamamoto T, Yano M, Cornea RL, Bers DM. Oda T, et al. Among authors: yang y. J Mol Cell Cardiol. 2015 Aug;85:240-8. doi: 10.1016/j.yjmcc.2015.06.009. Epub 2015 Jun 16. J Mol Cell Cardiol. 2015. PMID: 26092277 Free PMC article.

8

CaMKII-dependent phosphorylation of RyR2 promotes targetable pathological RyR2 conformational shift.

Uchinoumi H, Yang Y, Oda T, Li N, Alsina KM, Puglisi JL, Chen-Izu Y, Cornea RL, Wehrens XHT, Bers DM. Uchinoumi H, et al. Among authors: yang y. J Mol Cell Cardiol. 2016 Sep;98:62-72. doi: 10.1016/j.yjmcc.2016.06.007. Epub 2016 Jun 16. J Mol Cell Cardiol. 2016. PMID: 27318036 Free PMC article.

9

Size Matters: Ryanodine Receptor Cluster Size Heterogeneity Potentiates Calcium Waves.

Xie Y, Yang Y, Galice S, Bers DM, Sato D. Xie Y, et al. Among authors: yang y. Biophys J. 2019 Feb 5;116(3):530-539. doi: 10.1016/j.bpj.2018.12.017. Epub 2019 Jan 3. Biophys J. 2019. PMID: 30686487 Free PMC article.

10

Size Matters: Ryanodine Receptor Cluster Size Affects Arrhythmogenic Sarcoplasmic Reticulum Calcium Release.

Galice S, Xie Y, Yang Y, Sato D, Bers DM. Galice S, et al. Among authors: yang y. J Am Heart Assoc. 2018 Jun 21;7(13):e008724. doi: 10.1161/JAHA.118.008724. J Am Heart Assoc. 2018. PMID: 29929992 Free PMC article.

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