Di Cristofano A - Search Results

1

Modeling anaplastic thyroid carcinoma in the mouse.

Champa D, Di Cristofano A. Champa D, et al. Among authors: di cristofano a. Horm Cancer. 2015 Feb;6(1):37-44. doi: 10.1007/s12672-014-0208-8. Epub 2014 Nov 25. Horm Cancer. 2015. PMID: 25420535 Free PMC article. Review.

2

Obatoclax overcomes resistance to cell death in aggressive thyroid carcinomas by countering Bcl2a1 and Mcl1 overexpression.

Champa D, Russo MA, Liao XH, Refetoff S, Ghossein RA, Di Cristofano A. Champa D, et al. Among authors: di cristofano a. Endocr Relat Cancer. 2014 Oct;21(5):755-67. doi: 10.1530/ERC-14-0268. Epub 2014 Jul 10. Endocr Relat Cancer. 2014. PMID: 25012986 Free PMC article.

3

Obatoclax kills anaplastic thyroid cancer cells by inducing lysosome neutralization and necrosis.

Champa D, Orlacchio A, Patel B, Ranieri M, Shemetov AA, Verkhusha VV, Cuervo AM, Di Cristofano A. Champa D, et al. Among authors: di cristofano a. Oncotarget. 2016 Jun 7;7(23):34453-71. doi: 10.18632/oncotarget.9121. Oncotarget. 2016. PMID: 27144341 Free PMC article.

4

PI3K blockage synergizes with PLK1 inhibition preventing endoreduplication and enhancing apoptosis in anaplastic thyroid cancer.

De Martino D, Yilmaz E, Orlacchio A, Ranieri M, Zhao K, Di Cristofano A. De Martino D, et al. Among authors: di cristofano a. Cancer Lett. 2018 Dec 28;439:56-65. doi: 10.1016/j.canlet.2018.09.024. Epub 2018 Sep 19. Cancer Lett. 2018. PMID: 30243708 Free PMC article.

5

Establishment and characterization of cell lines from a novel mouse model of poorly differentiated thyroid carcinoma: powerful tools for basic and preclinical research.

Dima M, Miller KA, Antico-Arciuch VG, Di Cristofano A. Dima M, et al. Among authors: di cristofano a. Thyroid. 2011 Sep;21(9):1001-7. doi: 10.1089/thy.2011.0030. Epub 2011 Jul 18. Thyroid. 2011. PMID: 21767142 Free PMC article.

6

The PLK1 inhibitor GSK461364A is effective in poorly differentiated and anaplastic thyroid carcinoma cells, independent of the nature of their driver mutations.

Russo MA, Kang KS, Di Cristofano A. Russo MA, et al. Among authors: di cristofano a. Thyroid. 2013 Oct;23(10):1284-93. doi: 10.1089/thy.2013.0037. Epub 2013 Jul 25. Thyroid. 2013. PMID: 23509868 Free PMC article.

7

Thyrocyte-specific inactivation of p53 and Pten results in anaplastic thyroid carcinomas faithfully recapitulating human tumors.

Antico Arciuch VG, Russo MA, Dima M, Kang KS, Dasrath F, Liao XH, Refetoff S, Montagna C, Di Cristofano A. Antico Arciuch VG, et al. Among authors: di cristofano a. Oncotarget. 2011 Dec;2(12):1109-26. doi: 10.18632/oncotarget.380. Oncotarget. 2011. PMID: 22190384 Free PMC article.

8

SGK1 Is a Critical Component of an AKT-Independent Pathway Essential for PI3K-Mediated Tumor Development and Maintenance.

Orlacchio A, Ranieri M, Brave M, Arciuch VA, Forde T, De Martino D, Anderson KE, Hawkins P, Di Cristofano A. Orlacchio A, et al. Among authors: di cristofano a. Cancer Res. 2017 Dec 15;77(24):6914-6926. doi: 10.1158/0008-5472.CAN-17-2105. Epub 2017 Oct 20. Cancer Res. 2017. PMID: 29055016 Free PMC article.

9

PI3K/mTOR inhibition potentiates and extends palbociclib activity in anaplastic thyroid cancer.

Wong K, Di Cristofano F, Ranieri M, De Martino D, Di Cristofano A. Wong K, et al. Among authors: di cristofano a. Endocr Relat Cancer. 2019 Apr 1;26(4):425-436. doi: 10.1530/ERC-19-0011. Epub 2019 Jan 1. Endocr Relat Cancer. 2019. PMID: 30699064 Free PMC article.

10

Inhibition of AMPK and Krebs cycle gene expression drives metabolic remodeling of Pten-deficient preneoplastic thyroid cells.

Antico Arciuch VG, Russo MA, Kang KS, Di Cristofano A. Antico Arciuch VG, et al. Among authors: di cristofano a. Cancer Res. 2013 Sep 1;73(17):5459-72. doi: 10.1158/0008-5472.CAN-13-1429. Epub 2013 Jun 24. Cancer Res. 2013. PMID: 23796563 Free PMC article.

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