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Phase 1/2 study of valproic acid and short-course radiotherapy plus capecitabine as preoperative treatment in low-moderate risk rectal cancer-V-shoRT-R3 (Valproic acid--short Radiotherapy--rectum 3rd trial).
Avallone A, Piccirillo MC, Delrio P, Pecori B, Di Gennaro E, Aloj L, Tatangelo F, D'Angelo V, Granata C, Cavalcanti E, Maurea N, Maiolino P, Bianco F, Montano M, Silvestro L, Terranova Barberio M, Roca MS, Di Maio M, Marone P, Botti G, Petrillo A, Daniele G, Lastoria S, Iaffaioli VR, Romano G, Caracò C, Muto P, Gallo C, Perrone F, Budillon A. Avallone A, et al. Among authors: terranova barberio m. BMC Cancer. 2014 Nov 24;14:875. doi: 10.1186/1471-2407-14-875. BMC Cancer. 2014. PMID: 25421252 Free PMC article. Clinical Trial.
Valproic acid potentiates the anticancer activity of capecitabine in vitro and in vivo in breast cancer models via induction of thymidine phosphorylase expression.
Terranova-Barberio M, Roca MS, Zotti AI, Leone A, Bruzzese F, Vitagliano C, Scogliamiglio G, Russo D, D'Angelo G, Franco R, Budillon A, Di Gennaro E. Terranova-Barberio M, et al. Oncotarget. 2016 Feb 16;7(7):7715-31. doi: 10.18632/oncotarget.6802. Oncotarget. 2016. PMID: 26735339 Free PMC article.
Vorinostat synergizes with EGFR inhibitors in NSCLC cells by increasing ROS via up-regulation of the major mitochondrial porin VDAC1 and modulation of the c-Myc-NRF2-KEAP1 pathway.
Leone A, Roca MS, Ciardiello C, Terranova-Barberio M, Vitagliano C, Ciliberto G, Mancini R, Di Gennaro E, Bruzzese F, Budillon A. Leone A, et al. Among authors: terranova barberio m. Free Radic Biol Med. 2015 Dec;89:287-99. doi: 10.1016/j.freeradbiomed.2015.07.155. Epub 2015 Sep 26. Free Radic Biol Med. 2015. PMID: 26409771
Synthesis of Arylpiperazine Derivatives as Protease Activated Receptor 1 Antagonists and Their Evaluation as Antiproliferative Agents.
Zotti AI, Di Gennaro E, Corvino A, Frecentese F, Magli E, Perissutti E, Cirino G, Roviezzo F, Terranova-Barberio M, Iannelli F, Caliendo G, Santagada V, Fiorino F, Budillon A, Severino B. Zotti AI, et al. Among authors: terranova barberio m. Anticancer Agents Med Chem. 2017;17(7):973-981. doi: 10.2174/1871520616666160926120904. Anticancer Agents Med Chem. 2017. PMID: 27671294
HDAC inhibition potentiates immunotherapy in triple negative breast cancer.
Terranova-Barberio M, Thomas S, Ali N, Pawlowska N, Park J, Krings G, Rosenblum MD, Budillon A, Munster PN. Terranova-Barberio M, et al. Oncotarget. 2017 Dec 12;8(69):114156-114172. doi: 10.18632/oncotarget.23169. eCollection 2017 Dec 26. Oncotarget. 2017. PMID: 29371976 Free PMC article.
Host histone acetylation unlocks HDAC inhibitor potential.
Terranova-Barberio M, Thomas S, Munster PN. Terranova-Barberio M, et al. Oncotarget. 2017 Nov 13;8(63):106161-106162. doi: 10.18632/oncotarget.22422. eCollection 2017 Dec 5. Oncotarget. 2017. PMID: 29290932 Free PMC article. No abstract available.
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