Lourens HJ - Search Results

1

Kinase activity profiling reveals active signal transduction pathways in pediatric acute lymphoblastic leukemia: a new approach for target discovery.

van der Sligte NE, Scherpen FJ, Meeuwsen-de Boer TG, Lourens HJ, Ter Elst A, Diks SH, Guryev V, Peppelenbosch MP, van Leeuwen FN, de Bont ES. van der Sligte NE, et al. Among authors: lourens hj. Proteomics. 2015 Apr;15(7):1245-54. doi: 10.1002/pmic.201400286. Epub 2015 Jan 21. Proteomics. 2015. PMID: 25422122

2

Growth-factor-driven rescue to receptor tyrosine kinase (RTK) inhibitors through Akt and Erk phosphorylation in pediatric low grade astrocytoma and ependymoma.

Sie M, den Dunnen WF, Lourens HJ, Meeuwsen-de Boer TG, Scherpen FJ, Zomerman WW, Kampen KR, Hoving EW, de Bont ES. Sie M, et al. Among authors: lourens hj. PLoS One. 2015 Mar 23;10(3):e0122555. doi: 10.1371/journal.pone.0122555. eCollection 2015. PLoS One. 2015. PMID: 25799134 Free PMC article.

3

Exogenous HGF Bypasses the Effects of ErbB Inhibition on Tumor Cell Viability in Medulloblastoma Cell Lines.

Zomerman WW, Plasschaert SL, Diks SH, Lourens HJ, Meeuwsen-de Boer T, Hoving EW, den Dunnen WF, de Bont ES. Zomerman WW, et al. Among authors: lourens hj. PLoS One. 2015 Oct 23;10(10):e0141381. doi: 10.1371/journal.pone.0141381. eCollection 2015. PLoS One. 2015. PMID: 26496080 Free PMC article.

4

Peptide microarray profiling identifies phospholipase C gamma 1 (PLC-γ1) as a potential target for t(8;21) AML.

Mahmud H, Scherpen FJG, de Boer TM, Lourens HJ, Schoenherr C, Eder M, Scherr M, Guryev V, De Bont ES. Mahmud H, et al. Among authors: lourens hj. Oncotarget. 2017 Jun 27;8(40):67344-67354. doi: 10.18632/oncotarget.18631. eCollection 2017 Sep 15. Oncotarget. 2017. PMID: 28978037 Free PMC article.

5

Identification of Two Protein-Signaling States Delineating Transcriptionally Heterogeneous Human Medulloblastoma.

Zomerman WW, Plasschaert SLA, Conroy S, Scherpen FJ, Meeuwsen-de Boer TGJ, Lourens HJ, Guerrero Llobet S, Smit MJ, Slagter-Menkema L, Seitz A, Gidding CEM, Hulleman E, Wesseling P, Meijer L, van Kempen LC, van den Berg A, Warmerdam DO, Kruyt FAE, Foijer F, van Vugt MATM, den Dunnen WFA, Hoving EW, Guryev V, de Bont ESJM, Bruggeman SWM. Zomerman WW, et al. Among authors: lourens hj. Cell Rep. 2018 Mar 20;22(12):3206-3216. doi: 10.1016/j.celrep.2018.02.089. Cell Rep. 2018. PMID: 29562177 Free article.

6

CREB signaling activity correlates with differentiation and survival in medulloblastoma.

Armandari I, Zomerman WW, Plasschaert SLA, Smit MJ, Martini TEI, de Camargo Magalhães ES, Hogeling SM, Rozema-Huizinga GC, Lourens HJ, Meeuwsen-de Boer TGJ, Scherpen FJG, de Bont ESJM, Bruggeman SWM. Armandari I, et al. Among authors: lourens hj. Sci Rep. 2021 Aug 9;11(1):16077. doi: 10.1038/s41598-021-95381-0. Sci Rep. 2021. PMID: 34373489 Free PMC article.

7

Inhibition of Autophagy Does Not Re-Sensitize Acute Myeloid Leukemia Cells Resistant to Cytarabine.

Visser N, Lourens HJ, Huls G, Bremer E, Wiersma VR. Visser N, et al. Among authors: lourens hj. Int J Mol Sci. 2021 Feb 26;22(5):2337. doi: 10.3390/ijms22052337. Int J Mol Sci. 2021. PMID: 33652766 Free PMC article.

8

Galectin-9 has non-apoptotic cytotoxic activity toward acute myeloid leukemia independent of cytarabine resistance.

Choukrani G, Visser N, Ustyanovska Avtenyuk N, Olthuis M, Marsman G, Ammatuna E, Lourens HJ, Niki T, Huls G, Bremer E, Wiersma VR. Choukrani G, et al. Among authors: lourens hj. Cell Death Discov. 2023 Jul 6;9(1):228. doi: 10.1038/s41420-023-01515-w. Cell Death Discov. 2023. PMID: 37407572 Free PMC article.

9

EGFR-selective activation of CD27 co-stimulatory signaling by a bispecific antibody enhances anti-tumor activity of T cells.

Melo V, Nelemans LC, Vlaming M, Lourens HJ, Wiersma VR, Bilemjian V, Huls G, de Bruyn M, Bremer E. Melo V, et al. Among authors: lourens hj. Front Immunol. 2023 Jul 20;14:1191866. doi: 10.3389/fimmu.2023.1191866. eCollection 2023. Front Immunol. 2023. PMID: 37545491 Free PMC article.

10

CD20 positive CD8 T cells are a unique and transcriptionally-distinct subset of T cells with distinct transmigration properties.

Vlaming M, Bilemjian V, Freile JÁ, Lourens HJ, van Rooij N, Huls G, van Meerten T, de Bruyn M, Bremer E. Vlaming M, et al. Among authors: lourens hj. Sci Rep. 2021 Oct 15;11(1):20499. doi: 10.1038/s41598-021-00007-0. Sci Rep. 2021. PMID: 34654826 Free PMC article.

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