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Unlipidated outer membrane protein Omp16 (U-Omp16) from Brucella spp. as nasal adjuvant induces a Th1 immune response and modulates the Th2 allergic response to cow's milk proteins.
Ibañez AE, Smaldini P, Coria LM, Delpino MV, Pacífico LG, Oliveira SC, Risso GS, Pasquevich KA, Fossati CA, Giambartolomei GH, Docena GH, Cassataro J. Ibañez AE, et al. PLoS One. 2013 Jul 5;8(7):e69438. doi: 10.1371/journal.pone.0069438. Print 2013. PLoS One. 2013. PMID: 23861971 Free PMC article.
The protein moiety of Brucella abortus outer membrane protein 16 is a new bacterial pathogen-associated molecular pattern that activates dendritic cells in vivo, induces a Th1 immune response, and is a promising self-adjuvanting vaccine against systemic and oral acquired brucellosis.
Pasquevich KA, García Samartino C, Coria LM, Estein SM, Zwerdling A, Ibañez AE, Barrionuevo P, Oliveira FS, Carvalho NB, Borkowski J, Oliveira SC, Warzecha H, Giambartolomei GH, Cassataro J. Pasquevich KA, et al. Among authors: ibanez ae. J Immunol. 2010 May 1;184(9):5200-12. doi: 10.4049/jimmunol.0902209. Epub 2010 Mar 29. J Immunol. 2010. PMID: 20351187
An oral vaccine based on U-Omp19 induces protection against B. abortus mucosal challenge by inducing an adaptive IL-17 immune response in mice.
Pasquevich KA, Ibañez AE, Coria LM, García Samartino C, Estein SM, Zwerdling A, Barrionuevo P, Oliveira FS, Seither C, Warzecha H, Oliveira SC, Giambartolomei GH, Cassataro J. Pasquevich KA, et al. Among authors: ibanez ae. PLoS One. 2011 Jan 14;6(1):e16203. doi: 10.1371/journal.pone.0016203. PLoS One. 2011. PMID: 21264260 Free PMC article.
Brucella abortus induces apoptosis of human T lymphocytes.
Velásquez LN, Delpino MV, Ibañez AE, Coria LM, Miraglia MC, Scian R, Cassataro J, Giambartolomei GH, Barrionuevo P. Velásquez LN, et al. Among authors: ibanez ae. Microbes Infect. 2012 Jul;14(7-8):639-50. doi: 10.1016/j.micinf.2012.02.004. Epub 2012 Feb 23. Microbes Infect. 2012. PMID: 22387699 Free article.
A Brucella spp. Protease Inhibitor Limits Antigen Lysosomal Proteolysis, Increases Cross-Presentation, and Enhances CD8+ T Cell Responses.
Coria LM, Ibañez AE, Tkach M, Sabbione F, Bruno L, Carabajal MV, Berguer PM, Barrionuevo P, Schillaci R, Trevani AS, Giambartolomei GH, Pasquevich KA, Cassataro J. Coria LM, et al. Among authors: ibanez ae. J Immunol. 2016 May 15;196(10):4014-29. doi: 10.4049/jimmunol.1501188. Epub 2016 Apr 15. J Immunol. 2016. PMID: 27084100
A bacterial protease inhibitor protects antigens delivered in oral vaccines from digestion while triggering specific mucosal immune responses.
Ibañez AE, Coria LM, Carabajal MV, Delpino MV, Risso GS, Cobiello PG, Rinaldi J, Barrionuevo P, Bruno L, Frank F, Klinke S, Goldbaum FA, Briones G, Giambartolomei GH, Pasquevich KA, Cassataro J. Ibañez AE, et al. J Control Release. 2015 Dec 28;220(Pt A):18-28. doi: 10.1016/j.jconrel.2015.10.011. Epub 2015 Oct 9. J Control Release. 2015. PMID: 26456256 Free article.
Brucella abortus inhibits IFN-γ-induced FcγRI expression and FcγRI-restricted phagocytosis via toll-like receptor 2 on human monocytes/macrophages.
Barrionuevo P, Delpino MV, Velásquez LN, García Samartino C, Coria LM, Ibañez AE, Rodríguez ME, Cassataro J, Giambartolomei GH. Barrionuevo P, et al. Among authors: ibanez ae. Microbes Infect. 2011 Mar;13(3):239-50. doi: 10.1016/j.micinf.2010.10.020. Epub 2010 Nov 9. Microbes Infect. 2011. PMID: 21070860 Free article.
37 results