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Enhanced activation of an amino-terminally truncated isoform of the voltage-gated proton channel HVCN1 enriched in malignant B cells.
Hondares E, Brown MA, Musset B, Morgan D, Cherny VV, Taubert C, Bhamrah MK, Coe D, Marelli-Berg F, Gribben JG, Dyer MJ, DeCoursey TE, Capasso M. Hondares E, et al. Among authors: bhamrah mk. Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):18078-83. doi: 10.1073/pnas.1411390111. Epub 2014 Nov 25. Proc Natl Acad Sci U S A. 2014. PMID: 25425665 Free PMC article.
HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species.
Capasso M, Bhamrah MK, Henley T, Boyd RS, Langlais C, Cain K, Dinsdale D, Pulford K, Khan M, Musset B, Cherny VV, Morgan D, Gascoyne RD, Vigorito E, DeCoursey TE, MacLennan IC, Dyer MJ. Capasso M, et al. Among authors: bhamrah mk. Nat Immunol. 2010 Mar;11(3):265-72. doi: 10.1038/ni.1843. Epub 2010 Feb 7. Nat Immunol. 2010. PMID: 20139987 Free PMC article.