Elmquist WF - Search Results

1

Impact of BRAF mutation and BRAF inhibition on melanoma brain metastases.

Gummadi T, Zhang BY, Valpione S, Kim C, Kottschade LA, Mittapalli RK, Chiarion-Sileni V, Pigozzo J, Elmquist WF, Dudek AZ. Gummadi T, et al. Among authors: elmquist wf. Melanoma Res. 2015 Feb;25(1):75-9. doi: 10.1097/CMR.0000000000000133. Melanoma Res. 2015. PMID: 25426645

2

Altering distribution profile of palbociclib by its prodrugs.

Järvinen J, Montaser AB, Adla SK, Leppänen J, Lehtonen M, Vellonen KS, Laitinen T, Jalkanen A, Elmquist WF, Timonen J, Huttunen KM, Rautio J. Järvinen J, et al. Among authors: elmquist wf. Eur J Pharm Sci. 2024 Jan 1;192:106637. doi: 10.1016/j.ejps.2023.106637. Epub 2023 Nov 13. Eur J Pharm Sci. 2024. PMID: 37967656 Free article.

3

Central Nervous System Distribution of Panobinostat in Preclinical Models to Guide Dosing for Pediatric Brain Tumors.

Zhang W, Oh JH, Zhang W, Rathi S, Larson JD, Wechsler-Reya RJ, Sirianni RW, Elmquist WF. Zhang W, et al. Among authors: elmquist wf. J Pharmacol Exp Ther. 2023 Dec;387(3):315-327. doi: 10.1124/jpet.123.001826. Epub 2023 Oct 12. J Pharmacol Exp Ther. 2023. PMID: 37827699 Free PMC article.

4

Pharmacokinetics of panobinostat: Inter-species difference in metabolic stability.

Zhang W, Oh JH, Zhang W, Aldrich CC, Sirianni RW, Elmquist WF. Zhang W, et al. Among authors: elmquist wf. J Pharmacol Exp Ther. 2024 Feb 26;389(1):96-105. doi: 10.1124/jpet.123.002051. Online ahead of print. J Pharmacol Exp Ther. 2024. PMID: 38409112 Free article.

5

Quantitative proteomics of transporter expression in brain capillary endothelial cells isolated from P-glycoprotein (P-gp), breast cancer resistance protein (Bcrp), and P-gp/Bcrp knockout mice.

Agarwal S, Uchida Y, Mittapalli RK, Sane R, Terasaki T, Elmquist WF. Agarwal S, et al. Among authors: elmquist wf. Drug Metab Dispos. 2012 Jun;40(6):1164-9. doi: 10.1124/dmd.112.044719. Epub 2012 Mar 8. Drug Metab Dispos. 2012. PMID: 22401960 Free PMC article.

6

Impact of P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) on the brain distribution of a novel BRAF inhibitor: vemurafenib (PLX4032).

Mittapalli RK, Vaidhyanathan S, Sane R, Elmquist WF. Mittapalli RK, et al. Among authors: elmquist wf. J Pharmacol Exp Ther. 2012 Jul;342(1):33-40. doi: 10.1124/jpet.112.192195. Epub 2012 Mar 27. J Pharmacol Exp Ther. 2012. PMID: 22454535 Free PMC article.

7

Active efflux of Dasatinib from the brain limits efficacy against murine glioblastoma: broad implications for the clinical use of molecularly targeted agents.

Agarwal S, Mittapalli RK, Zellmer DM, Gallardo JL, Donelson R, Seiler C, Decker SA, Santacruz KS, Pokorny JL, Sarkaria JN, Elmquist WF, Ohlfest JR. Agarwal S, et al. Among authors: elmquist wf. Mol Cancer Ther. 2012 Oct;11(10):2183-92. doi: 10.1158/1535-7163.MCT-12-0552. Epub 2012 Aug 13. Mol Cancer Ther. 2012. PMID: 22891038 Free PMC article.

8

Mechanisms limiting distribution of the threonine-protein kinase B-RaF(V600E) inhibitor dabrafenib to the brain: implications for the treatment of melanoma brain metastases.

Mittapalli RK, Vaidhyanathan S, Dudek AZ, Elmquist WF. Mittapalli RK, et al. Among authors: elmquist wf. J Pharmacol Exp Ther. 2013 Mar;344(3):655-64. doi: 10.1124/jpet.112.201475. Epub 2012 Dec 17. J Pharmacol Exp Ther. 2013. PMID: 23249624 Free PMC article.

9

Brain metastases from renal cell carcinoma in the era of tyrosine kinase inhibitors.

Dudek AZ, Raza A, Chi M, Singhal M, Oberoi R, Mittapalli RK, Agarwal S, Elmquist WF. Dudek AZ, et al. Among authors: elmquist wf. Clin Genitourin Cancer. 2013 Jun;11(2):155-60. doi: 10.1016/j.clgc.2012.11.001. Epub 2012 Dec 21. Clin Genitourin Cancer. 2013. PMID: 23265925 Free PMC article.

10

Development and evaluation of a novel microemulsion formulation of elacridar to improve its bioavailability.

Sane R, Mittapalli RK, Elmquist WF. Sane R, et al. Among authors: elmquist wf. J Pharm Sci. 2013 Apr;102(4):1343-54. doi: 10.1002/jps.23450. Epub 2013 Jan 18. J Pharm Sci. 2013. PMID: 23334925 Free PMC article.

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