Sealover N - Search Results

1

Overexpression of Serpinb1 in Chinese hamster ovary cells increases recombinant IgG productivity.

Lin N, Brooks J, Sealover N, George HJ, Kayser KJ. Lin N, et al. Among authors: sealover n. J Biotechnol. 2015 Jan 10;193:91-9. doi: 10.1016/j.jbiotec.2014.10.040. Epub 2014 Nov 13. J Biotechnol. 2015. PMID: 25444873

2

Preselection of recombinant gene integration sites enabling high transcription rates in CHO cells using alternate start codons and recombinase mediated cassette exchange.

Baumann M, Gludovacz E, Sealover N, Bahr S, George H, Lin N, Kayser K, Borth N. Baumann M, et al. Among authors: sealover n. Biotechnol Bioeng. 2017 Nov;114(11):2616-2627. doi: 10.1002/bit.26388. Epub 2017 Aug 17. Biotechnol Bioeng. 2017. PMID: 28734047

3

Engineering Chinese hamster ovary (CHO) cells for producing recombinant proteins with simple glycoforms by zinc-finger nuclease (ZFN)-mediated gene knockout of mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (Mgat1).

Sealover NR, Davis AM, Brooks JK, George HJ, Kayser KJ, Lin N. Sealover NR, et al. J Biotechnol. 2013 Aug 10;167(1):24-32. doi: 10.1016/j.jbiotec.2013.06.006. Epub 2013 Jun 15. J Biotechnol. 2013. PMID: 23777858

4

Chinese hamster ovary (CHO) host cell engineering to increase sialylation of recombinant therapeutic proteins by modulating sialyltransferase expression.

Lin N, Mascarenhas J, Sealover NR, George HJ, Brooks J, Kayser KJ, Gau B, Yasa I, Azadi P, Archer-Hartmann S. Lin N, et al. Among authors: sealover nr. Biotechnol Prog. 2015 Mar-Apr;31(2):334-46. doi: 10.1002/btpr.2038. Epub 2015 Mar 1. Biotechnol Prog. 2015. PMID: 25641927 Free PMC article.

5

The GalNAc-type O-Glycoproteome of CHO cells characterized by the SimpleCell strategy.

Yang Z, Halim A, Narimatsu Y, Jitendra Joshi H, Steentoft C, Schjoldager KT, Alder Schulz M, Sealover NR, Kayser KJ, Paul Bennett E, Levery SB, Vakhrushev SY, Clausen H. Yang Z, et al. Mol Cell Proteomics. 2014 Dec;13(12):3224-35. doi: 10.1074/mcp.M114.041541. Epub 2014 Aug 4. Mol Cell Proteomics. 2014. PMID: 25092905 Free PMC article.

6

SOS1 Inhibition Enhances the Efficacy of KRASG12C Inhibitors and Delays Resistance in Lung Adenocarcinoma.

Daley BR, Sealover NE, Finniff BA, Hughes JM, Sheffels E, Gerlach D, Hofmann MH, Kostyrko K, LaMorte JP, Linke AJ, Beckley Z, Frank AM, Lewis RE, Wilkerson MD, Dalgard CL, Kortum RL. Daley BR, et al. Among authors: sealover ne. Cancer Res. 2025 Jan 2;85(1):118-133. doi: 10.1158/0008-5472.CAN-23-3256. Cancer Res. 2025. PMID: 39437166

7

Atlas of pacific sand lance (Ammodytes personatus) benthic habitat - Application of multibeam acoustics and directed sampling to identify viable subtidal substrates.

Baker MR, Greene HG, Aschoff J, Aitoro E, Bates E, Hesselroth D, Johnson K, Mather B, Sealover N. Baker MR, et al. Among authors: sealover n. Mar Environ Res. 2024 Nov;202:106778. doi: 10.1016/j.marenvres.2024.106778. Epub 2024 Oct 5. Mar Environ Res. 2024. PMID: 39378529

8

Protocol for modeling acquired resistance to targeted therapeutics in adherent and suspension cancer cell lines via in situ resistance assay.

Sealover NE, Hughes JM, Theard PL, Chatterjee D, Linke AJ, Finniff BA, Daley BR, Lewis RE, Kortum RL. Sealover NE, et al. STAR Protoc. 2024 Dec 20;5(4):103361. doi: 10.1016/j.xpro.2024.103361. Epub 2024 Oct 5. STAR Protoc. 2024. PMID: 39369385 Free PMC article.

9

Preclinical Therapeutic Efficacy of RAF/MEK/ERK and IGF1R/AKT/mTOR Inhibition in Neuroblastoma.

Stauffer S, Roth JS, Hernandez ER, Kowalczyk JT, Sealover NE, Hebron KE, James A, Isanogle KA, Riffle LA, Ileva L, Luo X, Chen JQ, Kedei N, Kortum RL, Lei H, Shern JF, Kalen JD, Edmondson EF, Hall MD, Difilippantonio S, Thiele CJ, Yohe ME. Stauffer S, et al. Among authors: sealover ne. Cancers (Basel). 2024 Jun 25;16(13):2320. doi: 10.3390/cancers16132320. Cancers (Basel). 2024. PMID: 39001383 Free PMC article.

10

In situ modeling of acquired resistance to RTK/RAS-pathway-targeted therapies.

Sealover NE, Theard PT, Hughes JM, Linke AJ, Daley BR, Kortum RL. Sealover NE, et al. iScience. 2023 Dec 11;27(1):108711. doi: 10.1016/j.isci.2023.108711. eCollection 2024 Jan 19. iScience. 2023. PMID: 38226159 Free PMC article.

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