Tasaki M - Search Results

1

Effect of AS2521780, a novel PKCθ selective inhibitor, on T cell-mediated immunity.

Fukahori H, Chida N, Maeda M, Tasaki M, Kawashima T, Matsuoka H, Suzuki K, Ishikawa T, Tanaka A, Higashi Y. Fukahori H, et al. Among authors: tasaki m. Eur J Pharmacol. 2014 Dec 15;745:217-22. doi: 10.1016/j.ejphar.2014.10.045. Epub 2014 Nov 6. Eur J Pharmacol. 2014. PMID: 25445039

2

Effect of novel PKCθ selective inhibitor AS2521780 on acute rejection in rat and non-human primate models of transplantation.

Fukahori H, Chida N, Maeda M, Tasaki M, Kawashima T, Noto T, Tsujimoto S, Nakamura K, Oshima S, Hirose J, Higashi Y, Morokata T. Fukahori H, et al. Among authors: tasaki m. Int Immunopharmacol. 2015 Aug;27(2):232-7. doi: 10.1016/j.intimp.2015.06.016. Epub 2015 Jun 26. Int Immunopharmacol. 2015. PMID: 26122135

3

A novel 2,4-diaminopyrimidine derivative as selective inhibitor of protein kinase C theta prevents allograft rejection in a rat heart transplant model.

Kunikawa S, Tanaka A, Takasuna Y, Tasaki M, Chida N. Kunikawa S, et al. Among authors: tasaki m. Bioorg Med Chem. 2018 Nov 1;26(20):5499-5509. doi: 10.1016/j.bmc.2018.09.029. Epub 2018 Sep 24. Bioorg Med Chem. 2018. PMID: 30274941

4

Discovery of 2,4-diamino-5-cyanopyrimidine derivatives as protein kinase C theta inhibitors with mitigated time-dependent drug-drug interactions.

Kunikawa S, Tanaka A, Takasuna Y, Tasaki M, Chida N. Kunikawa S, et al. Among authors: tasaki m. Bioorg Med Chem. 2019 Mar 1;27(5):790-799. doi: 10.1016/j.bmc.2019.01.019. Epub 2019 Jan 23. Bioorg Med Chem. 2019. PMID: 30704835

5

Optimization of 2,4-diamino-5-fluoropyrimidine derivatives as protein kinase C theta inhibitors with mitigated time-dependent drug-drug interactions and P-gp liability.

Kunikawa S, Tanaka A, Mukoyoshi K, Nagashima S, Tominaga H, Chida N, Tasaki M, Shirai F. Kunikawa S, et al. Among authors: tasaki m. Bioorg Med Chem. 2015 Jul 1;23(13):3269-77. doi: 10.1016/j.bmc.2015.04.050. Epub 2015 Apr 25. Bioorg Med Chem. 2015. PMID: 25982074

6

Inhibition of antigen-induced airway inflammation and hyperresponsiveness in guinea pigs by a selective antagonist of "chemoattractant receptor homologous molecule expressed on Th2 cells" (CRTH2).

Tasaki M, Kobayashi M, Tenda Y, Tsujimoto S, Nakazato S, Numazaki M, Hirano Y, Matsuda H, Terasaka T, Miyao Y, Shimizu Y, Hirayama Y. Tasaki M, et al. Eur J Pharm Sci. 2013 Jun 14;49(3):434-40. doi: 10.1016/j.ejps.2013.04.017. Epub 2013 Apr 24. Eur J Pharm Sci. 2013. PMID: 23624353

7

IL-7 coupled with IL-12 increases intratumoral T cell clonality, leading to complete regression of non-immunogenic tumors.

Tasaki M, Yamashita M, Arai Y, Nakamura T, Nakao S. Tasaki M, et al. Cancer Immunol Immunother. 2021 Dec;70(12):3557-3571. doi: 10.1007/s00262-021-02947-y. Epub 2021 Apr 28. Cancer Immunol Immunother. 2021. PMID: 33909103 Free PMC article.

8

Oncolytic vaccinia virus induces a novel phenotype of CD8⁺ effector T cells characterized by high ICOS expression.

Yamashita M, Tasaki M, Murakami R, Arai Y, Nakamura T, Nakao S. Yamashita M, et al. Among authors: tasaki m. Mol Ther Oncolytics. 2021 Feb 4;20:422-432. doi: 10.1016/j.omto.2021.01.016. eCollection 2021 Mar 26. Mol Ther Oncolytics. 2021. PMID: 33665362 Free PMC article.

9

Intratumoral expression of IL-7 and IL-12 using an oncolytic virus increases systemic sensitivity to immune checkpoint blockade.

Nakao S, Arai Y, Tasaki M, Yamashita M, Murakami R, Kawase T, Amino N, Nakatake M, Kurosaki H, Mori M, Takeuchi M, Nakamura T. Nakao S, et al. Among authors: tasaki m. Sci Transl Med. 2020 Jan 15;12(526):eaax7992. doi: 10.1126/scitranslmed.aax7992. Sci Transl Med. 2020. PMID: 31941828

10

High frequency of occult transthyretin and apolipoprotein AI-type amyloid in aortic valves removed by valve replacement for aortic stenosis.

Honda K, Tasaki M, Yamano T, Ueda M, Naiki H, Tanaka N, Morinaga Y, Miyagawa-Hayashino A. Honda K, et al. Among authors: tasaki m. Amyloid. 2024 Nov 11:1-7. doi: 10.1080/13506129.2024.2426508. Online ahead of print. Amyloid. 2024. PMID: 39526702 Free article.

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