Bourguignon JJ - Search Results

1

Inhibition of cyclic adenosine-3',5'-monophosphate phosphodiesterase from vascular smooth muscle by rolipram analogues.

Marivet MC, Bourguignon JJ, Lugnier C, Mann A, Stoclet JC, Wermuth CG. Marivet MC, et al. Among authors: bourguignon jj. J Med Chem. 1989 Jul;32(7):1450-7. doi: 10.1021/jm00127a009. J Med Chem. 1989. PMID: 2544722

2

Design, synthesis and structure-activity relationships of a series of 9-substituted adenine derivatives as selective phosphodiesterase type-4 inhibitors.

Raboisson P, Lugnier C, Muller C, Reimund JM, Schultz D, Pinna G, Le Bec A, Basaran H, Desaubry L, Gaudiot F, Seloum M, Bourguignon JJ. Raboisson P, et al. Among authors: bourguignon jj. Eur J Med Chem. 2003 Feb;38(2):199-214. doi: 10.1016/s0223-5234(02)01446-0. Eur J Med Chem. 2003. PMID: 12620664

3

3-aminopyridazine derivatives with atypical antidepressant, serotonergic, and dopaminergic activities.

Wermuth CG, Schlewer G, Bourguignon JJ, Maghioros G, Bouchet MJ, Moire C, Kan JP, Worms P, Biziere K. Wermuth CG, et al. Among authors: bourguignon jj. J Med Chem. 1989 Mar;32(3):528-37. doi: 10.1021/jm00123a004. J Med Chem. 1989. PMID: 2563772

4

Analogues of gamma-hydroxybutyric acid. Synthesis and binding studies.

Bourguignon JJ, Schoenfelder A, Schmitt M, Wermuth CG, Hechler V, Charlier B, Maitre M. Bourguignon JJ, et al. J Med Chem. 1988 May;31(5):893-7. doi: 10.1021/jm00400a001. J Med Chem. 1988. PMID: 3361576

5

9-Benzyladenines: potent and selective cAMP phosphodiesterase inhibitors.

Bourguignon JJ, Désaubry L, Raboisson P, Wermuth CG, Lugnier C. Bourguignon JJ, et al. J Med Chem. 1997 Jun 6;40(12):1768-70. doi: 10.1021/jm960827x. J Med Chem. 1997. PMID: 9191951 No abstract available.

6

5-HT3 antagonists derived from aminopyridazine-type muscarinic M1 agonists.

Rival Y, Hoffmann R, Didier B, Rybaltchenko V, Bourguignon JJ, Wermuth CG. Rival Y, et al. Among authors: bourguignon jj. J Med Chem. 1998 Jan 29;41(3):311-7. doi: 10.1021/jm9705418. J Med Chem. 1998. PMID: 9464362

7

Aminopyridazines as acetylcholinesterase inhibitors.

Contreras JM, Rival YM, Chayer S, Bourguignon JJ, Wermuth CG. Contreras JM, et al. Among authors: bourguignon jj. J Med Chem. 1999 Feb 25;42(4):730-41. doi: 10.1021/jm981101z. J Med Chem. 1999. PMID: 10052979

8

Design of small-sized libraries by combinatorial assembly of linkers and functional groups to a given scaffold: application to the structure-based optimization of a phosphodiesterase 4 inhibitor.

Krier M, Araújo-Júnior JX, Schmitt M, Duranton J, Justiano-Basaran H, Lugnier C, Bourguignon JJ, Rognan D. Krier M, et al. Among authors: bourguignon jj. J Med Chem. 2005 Jun 2;48(11):3816-22. doi: 10.1021/jm050063y. J Med Chem. 2005. PMID: 15916433

9

Cyclic nucleotide phosphodiesterase type 4 inhibitors: evaluation of pyrazolo[1,5-a]-1,3,5-triazine ring system as an adenine bioisostere.

Raboisson P, Schultz D, Muller C, Reimund JM, Pinna G, Mathieu R, Bernard P, Do QT, Desjarlais RL, Justiano H, Lugnier C, Bourguignon JJ. Raboisson P, et al. Among authors: bourguignon jj. Eur J Med Chem. 2008 Apr;43(4):816-29. doi: 10.1016/j.ejmech.2007.05.016. Epub 2007 Jun 8. Eur J Med Chem. 2008. PMID: 17640774

10

New PDE4 inhibitors based on pharmacophoric similarity between papaverine and tofisopam.

Bihel FJ, Justiniano H, Schmitt M, Hellal M, Ibrahim MA, Lugnier C, Bourguignon JJ. Bihel FJ, et al. Among authors: bourguignon jj. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6567-72. doi: 10.1016/j.bmcl.2011.08.036. Epub 2011 Aug 12. Bioorg Med Chem Lett. 2011. PMID: 21920746

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