Lugnier C - Search Results

1

Inhibition of cyclic adenosine-3',5'-monophosphate phosphodiesterase from vascular smooth muscle by rolipram analogues.

Marivet MC, Bourguignon JJ, Lugnier C, Mann A, Stoclet JC, Wermuth CG. Marivet MC, et al. Among authors: lugnier c. J Med Chem. 1989 Jul;32(7):1450-7. doi: 10.1021/jm00127a009. J Med Chem. 1989. PMID: 2544722

2

Design, synthesis and structure-activity relationships of a series of 9-substituted adenine derivatives as selective phosphodiesterase type-4 inhibitors.

Raboisson P, Lugnier C, Muller C, Reimund JM, Schultz D, Pinna G, Le Bec A, Basaran H, Desaubry L, Gaudiot F, Seloum M, Bourguignon JJ. Raboisson P, et al. Among authors: lugnier c. Eur J Med Chem. 2003 Feb;38(2):199-214. doi: 10.1016/s0223-5234(02)01446-0. Eur J Med Chem. 2003. PMID: 12620664

3

Design of small-sized libraries by combinatorial assembly of linkers and functional groups to a given scaffold: application to the structure-based optimization of a phosphodiesterase 4 inhibitor.

Krier M, Araújo-Júnior JX, Schmitt M, Duranton J, Justiano-Basaran H, Lugnier C, Bourguignon JJ, Rognan D. Krier M, et al. Among authors: lugnier c. J Med Chem. 2005 Jun 2;48(11):3816-22. doi: 10.1021/jm050063y. J Med Chem. 2005. PMID: 15916433

4

Cyclic nucleotide phosphodiesterase type 4 inhibitors: evaluation of pyrazolo[1,5-a]-1,3,5-triazine ring system as an adenine bioisostere.

Raboisson P, Schultz D, Muller C, Reimund JM, Pinna G, Mathieu R, Bernard P, Do QT, Desjarlais RL, Justiano H, Lugnier C, Bourguignon JJ. Raboisson P, et al. Among authors: lugnier c. Eur J Med Chem. 2008 Apr;43(4):816-29. doi: 10.1016/j.ejmech.2007.05.016. Epub 2007 Jun 8. Eur J Med Chem. 2008. PMID: 17640774

5

Cytosolic and membrane-bound cyclic nucleotide phosphodiesterases from guinea pig cardiac ventricles.

Muller B, Stoclet JC, Lugnier C. Muller B, et al. Among authors: lugnier c. Eur J Pharmacol. 1992 Mar 12;225(3):263-72. doi: 10.1016/0922-4106(92)90028-t. Eur J Pharmacol. 1992. PMID: 1325367

6

Cardiac cGMP-stimulated cyclic nucleotide phosphodiesterases: effects of cGMP analogues and drugs.

Komas N, Le Bec A, Stoclet JC, Lugnier C. Komas N, et al. Among authors: lugnier c. Eur J Pharmacol. 1991 Jan 25;206(1):5-13. doi: 10.1016/0922-4106(91)90140-d. Eur J Pharmacol. 1991. PMID: 1648496

7

Endothelium-dependent and independent relaxation of the rat aorta by cyclic nucleotide phosphodiesterase inhibitors.

Komas N, Lugnier C, Stoclet JC. Komas N, et al. Among authors: lugnier c. Br J Pharmacol. 1991 Oct;104(2):495-503. doi: 10.1111/j.1476-5381.1991.tb12457.x. Br J Pharmacol. 1991. PMID: 1665741 Free PMC article.

8

Involvement of rolipram-sensitive cyclic AMP phosphodiesterase in the regulation of cardiac contraction.

Muller B, Lugnier C, Stoclet JC. Muller B, et al. Among authors: lugnier c. J Cardiovasc Pharmacol. 1990 Nov;16(5):796-803. doi: 10.1097/00005344-199011000-00016. J Cardiovasc Pharmacol. 1990. PMID: 1703603

9

Role of cyclic AMP- and cyclic GMP-phosphodiesterases in the control of cyclic nucleotide levels and smooth muscle tone in rat isolated aorta. A study with selective inhibitors.

Schoeffter P, Lugnier C, Demesy-Waeldele F, Stoclet JC. Schoeffter P, et al. Among authors: lugnier c. Biochem Pharmacol. 1987 Nov 15;36(22):3965-72. doi: 10.1016/0006-2952(87)90465-5. Biochem Pharmacol. 1987. PMID: 2825708

10

9-Benzyladenines: potent and selective cAMP phosphodiesterase inhibitors.

Bourguignon JJ, Désaubry L, Raboisson P, Wermuth CG, Lugnier C. Bourguignon JJ, et al. Among authors: lugnier c. J Med Chem. 1997 Jun 6;40(12):1768-70. doi: 10.1021/jm960827x. J Med Chem. 1997. PMID: 9191951 No abstract available.

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